19 September 2020: Clinical Research
Risk Factor Analysis and Risk Prediction Model Construction of Pressure Injury in Critically Ill Patients with Cancer: A Retrospective Cohort Study in China
Zhong-Wen Sun ADG* , Min-Ru Guo BCE** , Li-Zi Yang DEF* , Ze-Jun Chen BCEF* , Zhu-Qing Zhang FDOI: 10.12659/MSM.926669
Med Sci Monit 2020; 26:e926669
Table 2 Univariate analysis of pressure injury (PI) occurrence in critically ill patients with cancer (n, %).
| Risk factors | PI | t/χ2 | P-value | ||
|---|---|---|---|---|---|
| None (n1=471) | Yes (n2=15) | ||||
| Age | 59.73±13.19 | 60.73±10.82 | −0.290 | 0.772 | |
| Gender | Female | 137 (97.86) | 3 (2.14) | 0.585 | 0.571 |
| Male | 334 (96.53) | 12 (3.47) | |||
| Length of stay in ICU | 18.65±12.80 | 26.00±19.32 | −1.463 | 0.165 | |
| APACHE II score | 12.46±5.50 | 19.60±6.59 | −4.914 | ||
| Waterlow score | 15.13±3.89 | 15.53±2.97 | −0.398 | 0.691 | |
| Shock | None | 434 (97.53) | 11 (2.47) | 6.659 | 0.030* |
| Yes | 37 (90.24) | 4 (9.76) | |||
| Respiratory failure | None | 330 (97.35) | 9 (2.65) | 0.698 | 0.402 |
| Yes | 141 (95.92) | 6 (4.08) | |||
| Bone marrow suppression | None | 450 (96.98) | 14 (3.02) | 0.164 | 0.506 |
| Yes | 21 (95.45) | 1 (4.55) | |||
| Cardiopulmonary resuscitation | None | 458 (97.24) | 13 (2.76) | 5.433 | 0.074 |
| Yes | 13 (86.67) | 2 (13.33) | |||
| Basic disease | None | 297 (96.43) | 11 (3.57) | 0.661 | 0.588 |
| Yes | 174 (97.75) | 4 (2.25) | |||
| Diabetes | None | 429 (97.06) | 13 (2.94) | 0.344 | 0.637 |
| Yes | 42 (95.45) | 2 (4.55) | |||
| History of radiotherapy | None | 389 (96.53) | 14 (3.47) | 0.485 | 0.242 |
| Yes | 82 (98.80) | 1 (1.20) | |||
| History of chemotherapy | None | 295 (98.01) | 6 (1.99) | 0.103 | 0.068 |
| Yes | 176 (95.14) | 9 (4.86) | |||
| Targeted therapy | None | 443 (97.15) | 13 (2.85) | 1.370 | 0.235 |
| Yes | 28 (93.33) | 2 (6.67) | |||
| Immunotherapy | None | 457 (97.03) | 14 (2.97) | 0.663 | 0.380 |
| Yes | 14 (93.33) | 1 (6.67) | |||
| Semi-reclining position | None | 197 (99.49) | 1 (0.51) | 7.744 | 0.006* |
| Yes | 274 (95.14) | 14 (4.86) | |||
| Mechanical ventilation | None | 73 (98.65) | 1 (1.35) | 0.879 | 0.712 |
| Yes | 398 (96.60) | 14 (3.40) | |||
| Enteral nutrition | None | 319 (98.46) | 5 (1.54) | 7.739 | 0.010* |
| Yes | 152 (93.83) | 10 (6.17) | |||
| CRRT | None | 449 (97.19) | 13 (2.81) | 2.324 | 0.166 |
| Yes | 22 (91.67) | 2 (8.33) | |||
| Sedative drugs | None | 231 (98.72) | 3 (1.28) | 4.912 | 0.034* |
| Yes | 240 (95.24) | 12 (4.76) | |||
| Analgesics drugs | None | 228 (97.44) | 6 (2.56) | 0.412 | 0.605 |
| Yes | 243 (96.43) | 9 (3.57) | |||
| Vasoactive drugs | None | 161 (99.38) | 1 (0.62) | 4.953 | 0.026* |
| Yes | 310 (95.68) | 14 (4.32) | |||
| Glucocorticoid | None | 376 (97.16) | 11 (2.84) | 0.378 | 0.520 |
| Yes | 95 (95.96) | 4 (4.04) | |||
| Recurrence fever | None | 413 (97.64) | 10 (2.36) | 5.692 | 0.033* |
| Yes | 58 (92.06) | 5 (7.94) | |||
| Lowing temperature by ice blanket | None | 440 (97.35) | 12 (2.65) | 4.023 | 0.080 |
| Yes | 31 (91.18) | 3 (8.82) | |||
| Hb | None | 426 (97.26) | 12 (2.74) | 1.782 | 0.177 |
| Yes | 45 (93.75) | 3 (6.25) | |||
| Hypoproteinemia | None | 334 (97.38) | 9 (2.62) | 0.834 | 0.392 |
| Yes | 137 (95.80) | 6 (4.20) | |||
| Diarrhea | None | 405 (98.30) | 7 (1.70) | 17.412 | |
| Yes | 66 (89.19) | 8 (10.81) | |||
| Humid skin | None | 398 (99.25) | 3 (0.75) | 41.910 | |
| Yes | 73 (85.88) | 12 (14.12) | |||
| Edema | None | 430 (98.40) | 7 (1.60) | 31.937 | |
| Yes | 41 (83.67) | 8 (16.33) | |||