Prognostic Value of Acute-On-Chronic Liver Failure (ACLF) Score in Critically Ill Patients with Cirrhosis and ACLF

26 September 2020: Database Analysis

Xinran Lin ^1ABCDEF* , Xielin Huang ^2ABCDEF* , Li Wang ^1BC , Shuyi Feng ^1B , Xiaofu Chen ^1BC , Weimin Cai ^1B , Zhiming Huang ^1A*

DOI: 10.12659/MSM.926574

Med Sci Monit 2020; 26:e926574

Table 6 Multivariate Cox regression analysis of the effect of AARC ACLF on 90-day mortality.

Variables	Unadjusted			Adjusted model I			Adjusted model II
Variables	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
AARC ACLF	1.434	1.335, 1.539		1.433	1.332, 1.542		1.375	1.247, 1.516
AARC ACLF grade
1	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference	Reference
2	2.922	2.012, 4.245		2.940	2.013, 4.293		1.949	1.201.3.163	0.002
3	6.295	4.119, 9.621		6.070	3.931, 9.373		4.432	2.591, 7.583
Adjust I model was adjusted for: age, sex, and ethnicity; adjust II model was adjusted for: age, sex, ethnicity, MAP, PaO2/FiO2, 24 h urine output, blood urea nitrogen, albumin, sodium, potassium, ventilator, white blood cell, vasopressor used, renal replacement therapy, variceal bleeding, ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome. CI – confidence interval; HR – hazard ratio.