26 September 2020>: Database Analysis
Prognostic Value of Acute-On-Chronic Liver Failure (ACLF) Score in Critically Ill Patients with Cirrhosis and ACLF
Xinran Lin 1ABCDEF* , Xielin Huang 2ABCDEF* , Li Wang 1BC , Shuyi Feng 1B , Xiaofu Chen 1BC , Weimin Cai 1B , Zhiming Huang 1A*DOI: 10.12659/MSM.926574
Med Sci Monit 2020; 26:e926574
Table 4 Diagnostic accuracy of scoring systems at cutoff points and at different time periods.
Prognostic models | 28-day AUROC | P value* | 90-day AUROC | P value* | 180-day AUROC | P value* |
---|---|---|---|---|---|---|
AARC ACLF | 0.754 | – | 0.747 | – | 0.728 | – |
Child-Pugh score | 0.688 | 0.692 | 0.673 | |||
MELD | 0.753 | 0.970 | 0.749 | 0.904 | 0.727 | 0.909 |
MELD-Na | 0.747 | 0.637 | 0.738 | 0.517 | 0.723 | 0.715 |
SOFA | 0.766 | 0.486 | 0.753 | 0.723 | 0.739 | 0.504 |
CLIF-SOFA | 0.743 | 0.459 | 0.745 | 0.878 | 0.727 | 0.888 |
CLIF-C ACLFs | 0.777 | 0.144 | 0.762 | 0.310 | 0.745 | 0.272 |
AUROC – area under the receiver operating characteristic curve; MELD – model for end-stage liver disease; SOFA – Sequential Organ Failure Assessment; CLIF-SOFA – Chronic Liver Failure-Sequential Organ Failure Assessment Score. * DeLong test was used to compare the performance of each scoring systems with AARC ACLF. |