07 January 2021>: Clinical Research
Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer
Dawei Ning 1BCEF , Kai Cui 2BC , Min Liu 2D , Yang Ou 3BCEF , Zhendan Wang 4B , Benkui Zou 5B , Yangyang Shen 6B , Xinyang Lu 7B , Sheng Li 8AG* , Pang Li 9AB*DOI: 10.12659/MSM.926565
Med Sci Monit 2021; 27:e926565
Table 9 Univariate and multivariate analyses of factors affecting overall survival in patients with gastric cancer.
Independent factors | Hazard ratio | 95% CI | P | Hazard ratio | 95% CI | P |
---|---|---|---|---|---|---|
CTC (CellSearch) (Yes/No) | 2.834 | 1.386–5.796 | 0.419 | 0.118–1.491 | 0.179 | |
CTC (≤3/>3) | 5.463 | 2.213–13.489 | 0.007 | 0.000–0.157 | ||
Age (≤60/>60) | 1.563 | 0.776–3.151 | 0.211 | |||
Sex (Male/Female) | 1.109 | 0.456–2.696 | 0.820 | |||
KPS (70–80/90–100) | 0.679 | 0.349–1.322 | 0.255 | |||
Platelet count | 1.001 | 0.997–1.005 | 0.627 | |||
N/L | 1.165 | 0.946–1.434 | 0.150 | |||
CEA ( | 1.382 | 0.821–2.327 | 0.224 | |||
CA199 ( | 1.092 | 0.668–1.785 | 0.726 | |||
Pathological stage (I–II/III–IV) | 10.670 | 2.538–44.849 | 4.756 | 0.799–28.319 | 0.087 | |
Distant metastasis (Yes/No) | 7.165 | 3.199–16.050 | 8.623 | 2.296–32.382 | ||
Lymph node metastasis (Yes/No) | 6.042 | 1.833–19.917 | 1.455 | 0.326–6.498 | 0.623 | |
Tumor size ( | 2.736 | 1.713–4.369 | 2.309 | 0.938–5.682 | 0.069 | |
Vascular invasion (Yes/No) | 1.917 | 1.246–2.951 | 0.480 | 0.197–1.171 | 0.107 |