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07 January 2021: Clinical Research

Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer

Dawei Ning 1BCEF , Kai Cui 2BC , Min Liu 2D , Yang Ou 3BCEF , Zhendan Wang 4B , Benkui Zou 5B , Yangyang Shen 6B , Xinyang Lu 7B , Sheng Li 8AG* , Pang Li 9AB*

DOI: 10.12659/MSM.926565

Med Sci Monit 2021; 27:e926565

Table 9 Univariate and multivariate analyses of factors affecting overall survival in patients with gastric cancer.

Independent factorsHazard ratio95% CIPHazard ratio95% CIP
CTC (CellSearch) (Yes/No)2.8341.386–5.7960.4190.118–1.4910.179
CTC (≤3/>3)5.4632.213–13.4890.0070.000–0.157
Age (≤60/>60)1.5630.776–3.1510.211
Sex (Male/Female)1.1090.456–2.6960.820
KPS (70–80/90–100)0.6790.349–1.3220.255
Platelet count1.0010.997–1.0050.627
N/L1.1650.946–1.4340.150
CEA (1.3820.821–2.3270.224
CA199 (1.0920.668–1.7850.726
Pathological stage (I–II/III–IV)10.6702.538–44.8494.7560.799–28.3190.087
Distant metastasis (Yes/No)7.1653.199–16.0508.6232.296–32.382
Lymph node metastasis (Yes/No)6.0421.833–19.9171.4550.326–6.4980.623
Tumor size (2.7361.713–4.3692.3090.938–5.6820.069
Vascular invasion (Yes/No)1.9171.246–2.9510.4800.197–1.1710.107

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750