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30 September 2020: Animal Study

Efficacy, Drug Sensitivity, and Safety of a Chronic Ocular Hypertension Rat Model Established Using a Single Intracameral Injection of Hydrogel into the Anterior Chamber

Huan Yu 1BCE* , Huimin Zhong 2CDF* , Junjue Chen 1DF , Jun Sun 1BF , Ping Huang 3EF , Xing Xu 3CE , Shouyue Huang 1ADE , Yisheng Zhong 1AG*

DOI: 10.12659/MSM.925852

Med Sci Monit 2020; 26:e925852

Table 1 Number of animals used in separate procedures (CECs sourced from the same eyes).

ProcedureNumberProcedureNumber
Flash Visual evoked potentials (F-VEP)112Histological analysis of anterior segment24
Ocular hypotensive drugs administration30Purification of corneal endothelial cells (CECs)24
CCK-8 assay of CECs24TUNEL assay of CECs24

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750