24 October 2020: Clinical Research
Retrospective Comparison of the Safety and Effectiveness of Dexmedetomidine Versus Standard of Care Before and During Cesarean Delivery in a Maternity Unit in Zhengzhou, China
Wei Zhao 1ABF , Ling Ma 1ABDF , Jingjing Wang 1EFG* , Xiaoyan Shi 2ABCFDOI: 10.12659/MSM.925709
Med Sci Monit 2020; 26:e925709
Table 4 Other maternal outcomes after delivery.
| Treatment cohorts | ||||
|---|---|---|---|---|
| DX: Dexmedetomidine before and during delivery + normal saline after delivery | SC: Normal saline before and during delivery + dexmedetomidine after delivery | CN: Normal saline before, during, and after delivery | ||
| No. women included | 115 | 109 | 168 | |
| Adverse effects | P values | |||
| Hypertension | 3 (3) | 7 (6) | 11 (7) | 0.297 |
| Hypotension | 5 (4) | 9 (8) | 14 (8) | 0.119 |
| Bradycardia | 4 (3) | 7 (6) | 9 (5) | 0.594 |
| Tachycardia | 1 (1) | 2 (2) | 3 (2) | 0.789 |
| Respiratory depression | 1 (1) | 1 (1) | 2 (1) | 0.958 |
| Hypoxia | 1 (1) | 1 (1) | 2 (1) | 0.958 |
| Wound sepsis | 1 (1) | 1 (1) | 2 (1) | 0.958 |
| Dry mouth | 5 (4) | 7 (6) | 18 (11) | 0.121 |
| Death | 0 (0) | 0 (0) | 1 (1) | 0.513 |
| Total adverse characteristics | 21 (18) | 35 (32) | 62 (37) | 0.998 |
| Data are shown as frequencies (percentages). Fisher’s exact test was performed for statistical analysis. P180 mmHg. Hypotension was defined as systolic blood pressure 10 min. Hypoxia was defined as peripheral capillary oxygen saturation | ||||