24 October 2020>: Clinical Research
Retrospective Comparison of the Safety and Effectiveness of Dexmedetomidine Versus Standard of Care Before and During Cesarean Delivery in a Maternity Unit in Zhengzhou, China
Wei Zhao 1ABF , Ling Ma 1ABDF , Jingjing Wang 1EFG* , Xiaoyan Shi 2ABCFDOI: 10.12659/MSM.925709
Med Sci Monit 2020; 26:e925709
Table 2 Measurement of pain during uterine contractions.
Treatment cohorts | |||||||
---|---|---|---|---|---|---|---|
DX: Dexmedetomidine before and during delivery + normal saline after delivery | SC: Normal saline before and during delivery + dexmedetomidine after delivery | CN: Normal saline before, during, and after delivery | |||||
No. women included | 115 | 109 | 168 | ||||
Time | q values | ||||||
P values | DX vs. SC | DX vs. CN | SC vs. SN | ||||
Immediately after delivery | 1.75±0.22 | 1.77±0.24 | 1.81±0.26 | 0.108 | N/A | N/A | N/A |
6 h after delivery | 3.47±0.24 | 3.55±0.26 | 3.51±0.28 | 0.077 | N/A | N/A | N/A |
12 h after delivery | 3.42±0.29 | 3.48±0.29 | 3.52±0.41 | 0.060 | N/A | N/A | N/A |
1 day after delivery | 2.23±0.15* | 2.31±0.17 | 2.38±0.21 | 6.931 | 9.569 | 1.883 | |
Data are shown as mean±SD. One-way analysis of variance was performed followed by Tukey’s post hoc test for statistical analysis. P3.326 were considered significant. * Significantly less than in the CN cohort. |