20 November 2020: Clinical Research
The Relationship Between Chronic Obstructive Pulmonary Disease and Cerebral Small Vessel Disease Assessed by Magnetic Resonance Imaging: A Case-Control Study from a Single Center in Beijing, China
Wei Qin 1ABCDE , Jiangmei Yin 2BCDF , Lei Yang 1BCF , Shuna Yang 1BF , Yue Li 1CE , Xuanting Li 1EG , Wenli Hu 1E*DOI: 10.12659/MSM.925703
Med Sci Monit 2020; 26:e925703
Table 2 Comparisons for individual cerebral small vessel disease (CSVD) imaging markers between chronic obstructive pulmonary disease (COPD) group and control group.
| CSVD imaging makers | COPD group (N=125) | Control group (N=130) | P | |
|---|---|---|---|---|
| WMH, n (%) | Mild (0–2) | 25 (20.0) | 56 (43.1) | |
| Moderate (3–4) | 53 (42.4) | 44 (33.8) | ||
| Severe (5–6) | 47 (37.6) | 30 (23.1) | ||
| BG-EPVS, n (%) | 1 | 71 (56.8) | 42 (32.3) | 0.001 |
| 2 | 14 (11.2) | 18 (13.8) | ||
| 3 | 22 (17.6) | 34 (26.2) | ||
| 4 | 18 (14.4) | 36 (27.7) | ||
| CSO-EPVS, n (%) | 1 | 120 (96.0) | 72 (55.4) | |
| 2 | 1 (0.8) | 22 (16.9) | ||
| 3 | 2 (1.6) | 15 (11.5) | ||
| 4 | 2 (1.6) | 21 (16.2) | ||
| Brain atrophy, n (%) | 0 | 35 (28.0) | 38 (29.2) | 0.537 |
| 1 | 57 (45.6) | 53 (40.8) | ||
| 2 | 22 (17.6) | 31 (23.8) | ||
| 3 | 11 (8.8) | 8 (6.2) | ||
| WMH – white matter hyperintensities; BG-EPVS – basal ganglia enlarged perivascular spaces; CSO-EPVS – centrum semiovale enlarged perivascular spaces. | ||||