20 November 2020: Clinical Research
The Relationship Between Chronic Obstructive Pulmonary Disease and Cerebral Small Vessel Disease Assessed by Magnetic Resonance Imaging: A Case-Control Study from a Single Center in Beijing, China
Wei Qin 1ABCDE , Jiangmei Yin 2BCDF , Lei Yang 1BCF , Shuna Yang 1BF , Yue Li 1CE , Xuanting Li 1EG , Wenli Hu 1E*DOI: 10.12659/MSM.925703
Med Sci Monit 2020; 26:e925703
Table 1 General characteristics of chronic obstructive pulmonary disease (COPD) group and control group.
| Characteristics | COPD group (N=125) | Control group (N=130) | P |
|---|---|---|---|
| Age, years | 69.62±11.46 | 68.01±9.66 | 0.224 |
| Male, n (%) | 82 (65.6) | 85 (65.4) | 0.971 |
| Hypertension, n (%) | 57 (45.6) | 95 (73.1) | |
| DM, n (%) | 25 (20.0) | 60 (46.2) | |
| History of stroke, n (%) | 12 (9.6) | 42 (32.3) | |
| History of CHD, n (%) | 14 (11.2) | 25 (19.2) | 0.075 |
| Alcoholism, n (%) | 21 (16.8) | 27 (20.8) | 0.418 |
| Smoking, n (%) | 77 (61.6) | 49 (37.7) | |
| HbA1c, % | 5.92±1.39 | 5.62±1.27 | 0.072 |
| TC, mmol/L | 4.18 (3.71, 4.94) | 4.20 (3.57, 4.99) | 0.939 |
| LDL-C, mmol/L | 2.43 (2.06, 2.87) | 2.40 (1.80, 3.20) | 0.852 |
| ESR, mmol/L | 12.00 (5.00, 24.50) | 9.00 (5.00, 14.00) | 0.012 |
| HDL-C, mmol/L | 1.18 (0.99, 1.50) | 1.13 (0.90, 1.30) | 0.086 |
| Cr, mmol/L | 75.86±28.70 | 74.21±40.96 | 0.712 |
| CRP, mmol/L | 0.75 (0.36, 2.52) | 0.35 (0.30, 0.70) | |
| Data are presented as mean±standard deviation, median (interquartile range) or counts (%). DM – diabetes mellitus; CHD – coronary heart disease; HbA1c – glycosylated hemoglobin; TC – total cholesterol; LDL-C – low density lipoprotein cholesterol; ESR – erythrocyte sedimentation rate; HDL-C – high density lipoprotein cholesterol; Cr – creatinine; CRP – C-reactive protein. | |||