01 October 2020: Database Analysis
, , and Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis
Liuxun Li 1ABCDEF , Meiling Yang 2BCDEF , Anmin Jin 1ABCDEFG*DOI: 10.12659/MSM.925474
Med Sci Monit 2020; 26:e925474
Table 2 Top 10 core genes related to focal adhesion in gene set enrichment analysis (GSEA) details.
| Rank | Gene | Rank in gene list | Rank metric score | Running ES | Core enrichment |
|---|---|---|---|---|---|
| 1 | 11 | 0.466370821 | 0.04158658 | Yes | |
| 2 | 22 | 0.402014107 | 0.07741158 | Yes | |
| 3 | 28 | 0.381570011 | 0.11161295 | Yes | |
| 4 | 38 | 0.360972673 | 0.14377967 | Yes | |
| 5 | 45 | 0.338007063 | 0.17400703 | Yes | |
| 6 | 59 | 0.30732277 | 0.20115735 | Yes | |
| 7 | 61 | 0.307254642 | 0.22883116 | Yes | |
| 8 | 78 | 0.288572252 | 0.25415757 | Yes | |
| 9 | 98 | 0.265819669 | 0.277299 | Yes | |
| 10 | 140 | 0.221685633 | 0.29548803 | Yes | |
| ES – enrichment score; COL3A1 – collagen type III alpha 1 chain; TNN – tenascin N; COL5A1 – collagen type V alpha 1 chain; ITGB6 – integrin subunit beta 6; THBS4 – thrombospondin 4; COL5A2 – collagen type V alpha 2 chain; IGF1 – insulin like growth factor 1; COL6A3 – collagen type VI alpha 3 chain; THBS2 – thrombospondin 2; COL1A2 – collagen type I alpha 2 chain. | |||||