23 July 2020>: Database Analysis
Identification of Biomarkers for Sarcoidosis and Tuberculosis of the Lung Using Systematic and Integrated Analysis
Min Zhao 1ABCEF , Xin Di 1BCE , Xin Jin 2CDE , Chang Tian 1BF , Shan Cong 1CF , Jiangyin Liu 1BF , Ke Wang 1ABDEG*DOI: 10.12659/MSM.925438
Med Sci Monit 2020; 26:e925438
Table 4 GO analysis of SARC-PTB common DEGs.
Category | Term | Count | % | P-value | FDR |
---|---|---|---|---|---|
GOTERM_BP_DIRECT | GO: 0060333~interferon-gamma-mediated signaling pathway | 4 | 0.05 | 0.00138 | 1.94609 |
GOTERM_BP_DIRECT | GO: 0010332~response to gamma radiation | 3 | 0.03 | 0.00413 | 5.71893 |
GOTERM_BP_DIRECT | GO: 0006955~immune response | 6 | 0.07 | 0.00956 | 12.77981 |
GOTERM_BP_DIRECT | GO: 0042542~response to hydrogen peroxide | 3 | 0.03 | 0.01088 | 14.42335 |
GOTERM_BP_DIRECT | GO: 0006952~defense response | 3 | 0.03 | 0.01829 | 23.10506 |
GOTERM_BP_DIRECT | GO: 0007584~response to nutrient | 3 | 0.03 | 0.02204 | 27.18070 |
GOTERM_BP_DIRECT | GO: 0007165~signal transduction | 9 | 0.10 | 0.02538 | 30.63884 |
GOTERM_BP_DIRECT | GO: 0006915~apoptotic process | 6 | 0.07 | 0.03045 | 35.60432 |
GOTERM_BP_DIRECT | GO: 0060334~regulation of interferon-gamma-mediated signaling pathway | 2 | 0.02 | 0.03953 | 43.67413 |
GOTERM_BP_DIRECT | GO: 0008631~intrinsic apoptotic signaling pathway in response to oxidative stress | 2 | 0.02 | 0.04548 | 48.43701 |
GOTERM_CC_DIRECT | GO: 0016020~membrane | 13 | 0.15 | 0.02196 | 22.02011 |
GOTERM_MF_DIRECT | GO: 0042803~protein homodimerization activity | 7 | 0.08 | 0.02208 | 23.23086 |
GOTERM_MF_DIRECT | GO: 0004871~signal transducer activity | 4 | 0.05 | 0.02368 | 24.71270 |
GOTERM_MF_DIRECT | GO: 0008509~anion transmembrane transporter activity | 2 | 0.02 | 0.02687 | 27.57188 |
Go – Gene Ontology; DEGs – differentially expressed genes; SARC – sarcoidosis; PTB – pulmonary tuberculosis; FDR – false discovery rate. |