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23 July 2020: Database Analysis

Identification of Biomarkers for Sarcoidosis and Tuberculosis of the Lung Using Systematic and Integrated Analysis

Min Zhao 1ABCEF , Xin Di 1BCE , Xin Jin 2CDE , Chang Tian 1BF , Shan Cong 1CF , Jiangyin Liu 1BF , Ke Wang 1ABDEG*

DOI: 10.12659/MSM.925438

Med Sci Monit 2020; 26:e925438

Table 4 GO analysis of SARC-PTB common DEGs.

CategoryTermCount%P-valueFDR
GOTERM_BP_DIRECTGO: 0060333~interferon-gamma-mediated signaling pathway40.050.001381.94609
GOTERM_BP_DIRECTGO: 0010332~response to gamma radiation30.030.004135.71893
GOTERM_BP_DIRECTGO: 0006955~immune response60.070.0095612.77981
GOTERM_BP_DIRECTGO: 0042542~response to hydrogen peroxide30.030.0108814.42335
GOTERM_BP_DIRECTGO: 0006952~defense response30.030.0182923.10506
GOTERM_BP_DIRECTGO: 0007584~response to nutrient30.030.0220427.18070
GOTERM_BP_DIRECTGO: 0007165~signal transduction90.100.0253830.63884
GOTERM_BP_DIRECTGO: 0006915~apoptotic process60.070.0304535.60432
GOTERM_BP_DIRECTGO: 0060334~regulation of interferon-gamma-mediated signaling pathway20.020.0395343.67413
GOTERM_BP_DIRECTGO: 0008631~intrinsic apoptotic signaling pathway in response to oxidative stress20.020.0454848.43701
GOTERM_CC_DIRECTGO: 0016020~membrane130.150.0219622.02011
GOTERM_MF_DIRECTGO: 0042803~protein homodimerization activity70.080.0220823.23086
GOTERM_MF_DIRECTGO: 0004871~signal transducer activity40.050.0236824.71270
GOTERM_MF_DIRECTGO: 0008509~anion transmembrane transporter activity20.020.0268727.57188
Go – Gene Ontology; DEGs – differentially expressed genes; SARC – sarcoidosis; PTB – pulmonary tuberculosis; FDR – false discovery rate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750