01 October 2020: Database Analysis
Comparison of Bispectral Index-Guided Individualized Anesthesia with Standard General Anesthesia on Inadequate Emergence and Postoperative Delirium in Elderly Patients Undergoing Esophagectomy: A Retrospective Study at a Single Center
Yichen Yang 1ACDEF* , Chengjun Song 2BCDEF* , Chengwei Song 2ACDEF , Chengwen Li 3ACDEFG*DOI: 10.12659/MSM.925314
Med Sci Monit 2020; 26:e925314
Table 3 Comparison of emergence after anesthesia and postoperative delirium (PD) between groups before and after propensity score matching.
| Variable | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
| Group I (n=66) | Group S (n=95) | P-value | Group I (n=58) | Group S (n=58) | P-value | |
| Eye-opening time, min1 | 11 (8–15) | 15 (12–20) | 0.000 | 11 (8–15) | 16 (12–20) | 0.000 |
| Extubation time, min2 | 12.5 (9–16) | 17 (13–22) | 0.000 | 13 (9–17) | 17 (14–20) | 0.000 |
| Inadequate emergence | 20 (30.3) | 41 (43.2) | 0.098 | 18 (31.0) | 25 (43.1) | 0.178 |
| Emergence agitation, n (%)3 | 18 (27.3) | 35 (36.8) | 0.204 | 14 (24.1) | 20 (34.5) | 0.221 |
| Delayed emergence, n (%)4 | 4 (6.1) | 6 (6.3) | 1.000 | 4 (6.9) | 5 (8.6) | 1.000 |
| Postoperative delirium, n (%) | 9 (13.6) | 20 (21.1) | 0.228 | 7 (12.1) | 12 (20.7) | 0.210 |
| Values are expressed as median (IQR) or n (%). Groups: I, BIS indices maintained at about 10 less than the BIS value at LOC; S, BIS indices maintained at 40–60. PD – postoperative delirium; BIS – bispectral index; LOC – loss of consciousness, SAS – Riker sedation-agitation scale; PACU – postanesthetic care unit. 1 Eye-opening time: the time from the termination of propofol infusion to eye-opening on verbal command; 2 Extubation time: the time from the termination of propofol infusion to the tube removal out of the tracheal; 3 Emergence agitation: SAS score ≥5 at 1 min after extubation and in PACU; 4 Delayed emergence: duration ≥30 min with SAS score ≤2 from termination of propofol infusion. | ||||||