18 October 2020: Clinical Research
Expression of Matrix Metalloproteinase-2, Matrix Metalloproteinase-9, Tissue Inhibitor of Metalloproteinase-1, and Changes in Alveolar Septa in Patients with Chronic Obstructive Pulmonary Disease
Yongxiang Zhang ABCDE , Yuechuan Li AEFG* , Zhen Ye BD , Hui Ma CFDOI: 10.12659/MSM.925278
Med Sci Monit 2020; 26:e925278
Table 5 Correlation between alveolar septum thickness and fiber composition ratio and lung function.
| r (P) | Linear correlation coefficient | ||
|---|---|---|---|
| Thickness (um) | Collagenous fiber (%) | Elastic fibers (%) | |
| FEV | −0.245 (0.06) | −0.360 (0.005) | 0.231 (0.076) |
| FVC | −0.206 (0.115) | −0.224 (0.085) | −0.051 (0.699) |
| FEV/FVC | −0.170 (0.193) | −0.267 (0.04) | 0.373 (0.003) |
| FEVv%pre | −0.335 (0.035) | −0.472 (0.002) | 0.316 (0.047) |
| DLCO%pre | −0.078 (0.554) | −0.329 (0.010) | 0.316 (0.014) |
| FEV – forced expiratory volume in 1 second; FVC – forced vital capacity; DLCO – carbon monoxide diffusing capacity. | |||