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13 September 2020: Database Analysis

Nomogram for Predicting Breast Cancer-Specific Mortality of Elderly Women with Breast Cancer

Xunxi Lu 12ABCDEF* , Xiaoguang Li 1ADEFG* , Hong Ling 12DFG , Yue Gong 12ACD , Linwei Guo 12ACE , Min He 12DF , Hefen Sun 12DG , Xin Hu 12EFG*

DOI: 10.12659/MSM.925210

Med Sci Monit 2020; 26:e925210

Table 2 5-, 8-, 10-Year cumulative incidences of BCSD among patients with breast cancer in the training cohort.

CharacteristicsBCSD
Events (%)5-y (%)8-y (%)10-y (%)P-value
Total1748 (100.0)5.78.19.2
Age
 65–74981 (56.1)4.67.08.2
 75+767 (43.9)7.610.111.0
Marriage
 Unmarried325 (18.6)7.510.611.6
 Married1423 (81.4)5.47.78.8
Race
 White1475 (84.4)5.57.99.0
 Black166 (9.5)9.412.713.4
 Other* 107 (6.1)5.07.28.1
Histology
 IDC1326 (75.9)6.28.59.6
 ILC172 (9.8)5.09.211.3
 Other** 250 (14.3)4.36.26.9
Grade
 I138 (7.9)1.32.42.7
 II648 (37.1)4.06.47.8
 III/IV962 (55.0)12.816.417.7
Laterality0.170
 Left919 (52.6)5.88.39.6
 Right829 (47.4)5.67.98.8
ER status
 Negative611 (35.0)15.018.018.8
 Positive1137 (65.0)3.96.27.4
PR status
 Negative877 (50.2)11.514.415.4
 Positive871 (49.8)3.45.66.7
T stage
 T1587 (33.6)2.53.94.6
 T2811 (46.4)10.614.916.5
 T3193 (11.0)20.628.031.4
 T4157 (9.0)30.338.539.7
N stage
 N0688 (39.4)2.84.35.0
 N1561 (32.1)9.914.015.8
 N2257 (14.7)19.826.929.6
 N3242 (13.8)32.342.847.0
Surgery
 BCS719 (41.1)3.55.06.0
 Mastectomy1029 (58.9)9.913.915.2
IDC – infiltrating ductal carcinoma; ILC – infiltrating lobular carcinoma; ER – estrogen receptor; PR – progesterone receptor; BCS – breast-conserving surgery; BCSD – breast cancer-specific death; OCSD – other cause-specific death; T – tumor stage; N – nearby lymph node stage.
* Including American Indian/Alaskan native and Pacific Islander;
** including other histology of invasive breast cancer except IDC and ILC.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750