TPX2 Promotes Metastasis and Serves as a Marker of Poor Prognosis in Non-Small Cell Lung Cancer

Fang Zhou; Meng Wang; Mijiti Aibaidula; Zhiguo Zhang; Abudusaimaiti Aihemaiti; Rezhake Aili; Hao Chen; Shuangfeng D Dong; Wei Wei; Abulizi Maimaitiaili

doi:10.12659/MSM.925147

04 August 2020: Database Analysis

TPX2 Promotes Metastasis and Serves as a Marker of Poor Prognosis in Non-Small Cell Lung Cancer

Fang Zhou ^1ACE , Meng Wang ^1D , Mijiti Aibaidula ^2F , Zhiguo Zhang ^2D , Abudusaimaiti Aihemaiti ^2B , Rezhake Aili ^2B , Hao Chen ^2B , Shuangfeng Dong ^2B , Wei Wei ^2B , Abulizi Maimaitiaili ^2ACG*

DOI: 10.12659/MSM.925147

Med Sci Monit 2020; 26:e925147

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Supplementary Table 1 The TCGA and Protein Atlas – downloaded data.

Sample	FPKM TPX2	AJCC pathologic m	AJCC pathologic n
TCGA-78-7167	0.8	M1	N0
TCGA-49-4510	1.1	M0	N1
TCGA-55-8512	1.2	M1b	N1
TCGA-86-A4P8	1.2	MX	N2
TCGA-78-7156	1.5	M1	N1
TCGA-91-6849	1.7	MX	N2
TCGA-67-6217	1.9	M0	N1
TCGA-91-A4BD	2.1	MX	N1
TCGA-NJ-A7XG	2.2	M0	N1
TCGA-05-4384	2.6	M0	N2
TCGA-MP-A4T6	3.2	MX	N2
TCGA-05-5423	3.3	M0	N1
TCGA-64-1680	3.4	M1	N2
TCGA-44-2659	3.6	M0	N1
TCGA-L9-A50W	3.6	MX	N1
TCGA-49-4505	3.7	M0	N1
TCGA-69-8253	4	MX	N1
TCGA-NJ-A4YI	4	M0	N2
TCGA-50-5068	4.3	MX	N1
TCGA-86-7714	4.4	M0	N2
TCGA-J2-8192	4.5	MX	N1
TCGA-75-6212	4.6	M0	N1
TCGA-49-4490	4.8	M0	N2
TCGA-44-2665	5.1	M0	N1
TCGA-NJ-A55O	5.3	M0	N1
TCGA-38-4627	5.4	M0	N1
TCGA-55-6983	5.7	M0	N1
TCGA-55-7227	5.7	MX	N1
TCGA-73-4675	5.7	M0	N1
TCGA-97-8171	5.8	M1a	N2
TCGA-50-5055	5.9	M0	N1
TCGA-86-8671	6.3	M0	N1
TCGA-86-8674	6.3	M0	N1
TCGA-86-8359	6.4	M0	N2
TCGA-50-5932	6.5	M0	N1
TCGA-86-8278	6.6	M0	N1
TCGA-49-6744	6.9	MX	N1
TCGA-78-7158	7.3	M0	N2
TCGA-05-5428	7.4	M0	N1
TCGA-50-5045	7.5	M0	N1
TCGA-49-4506	7.8	M0	N1
TCGA-62-A46Y	7.8	M0	N2
TCGA-97-8547	8.2	MX	N2
TCGA-38-4628	8.3	M0	N1
TCGA-05-4396	8.6	M0	N1
TCGA-55-7283	8.6	MX	N2
TCGA-MP-A4TD	8.6	M0	N2
TCGA-53-7626	9.3	M0	N1
TCGA-55-6984	9.3	M0	N1
TCGA-95-A4VK	9.3	M0	N2
TCGA-49-4512	9.4	MX	N2
TCGA-55-7914	9.4	MX	N1
TCGA-55-A48X	9.5	M0	N1
TCGA-05-5420	9.6	M0	N2
TCGA-55-8094	10.2	M1b	N0
TCGA-MP-A4T9	10.2	MX	N2
TCGA-78-7160	10.3	M1	N2
TCGA-91-6830	10.7	MX	N1
TCGA-05-4402	10.9	M1	NX
TCGA-05-4425	11.1	M1	N0
TCGA-86-8279	11.1	M0	N1
TCGA-93-A4JP	11.3	M1b	NX
TCGA-55-8615	11.3	MX	N2
TCGA-44-6774	11.6	M0	N2
TCGA-49-AAQV	11.6	MX	N1
TCGA-97-7554	11.6	M0	N2
TCGA-05-4418	12	M0	N2
TCGA-50-5051	12	M0	N2
TCGA-55-8508	12	MX	N1
TCGA-05-5429	12.3	M0	N2
TCGA-50-5930	12.8	M0	N2
TCGA-64-5815	13	M0	N1
TCGA-L9-A5IP	13.1	M1b	N2
TCGA-78-7148	13.1	M0	N1
TCGA-55-7907	13.3	MX	N1
TCGA-86-6851	13.4	M0	N1
TCGA-MP-A4SY	13.5	M0	N1
TCGA-MP-A4T8	13.5	M0	N2
TCGA-55-8505	13.7	MX	N2
TCGA-MP-A4SW	13.8	M0	N1
TCGA-73-4659	13.9	M0	N2
TCGA-50-6593	14	M0	N2
TCGA-86-8055	14.2	M0	N1
TCGA-78-7166	14.4	M0	N1
TCGA-L9-A7SV	14.4	M0	N1
TCGA-55-6981	14.5	M0	N2
TCGA-95-A4VP	14.7	M0	N2
TCGA-L9-A743	14.7	M0	N1
TCGA-44-3396	14.8	M0	N2
TCGA-78-7147	15	M0	N1
TCGA-95-7567	15	M0	N1
TCGA-55-6970	15.3	MX	N2
TCGA-55-6982	15.4	M0	N1
TCGA-99-8025	15.5	M0	N2
TCGA-MP-A4T7	16	M1	N0
TCGA-49-AAR4	16.2	MX	N2
TCGA-55-A48Z	17.4	MX	N3
TCGA-55-6712	17.8	MX	N1
TCGA-64-1679	18	M0	N2
TCGA-49-6745	18.3	M0	N2
TCGA-62-8398	18.3	M0	N2
TCGA-49-4494	18.6	M0	N2
TCGA-78-8640	18.8	M0	N1
TCGA-86-8074	18.8	M0	N1
TCGA-78-7145	19.3	M1	N1
TCGA-99-8033	19.4	M1	NX
TCGA-86-6562	19.5	M0	N1
TCGA-73-4668	19.7	M0	N1
TCGA-05-4434	20	M1	N1
TCGA-49-6761	20.7	MX	N2
TCGA-69-7974	21.1	MX	N2
TCGA-MP-A4TK	21.2	MX	N1
TCGA-38-4632	21.4	M1	N1
TCGA-64-5779	21.6	M0	N2
TCGA-50-5941	21.8	M0	N2
TCGA-73-4676	21.8	M0	N1
TCGA-62-8399	21.9	M0	N2
TCGA-MN-A4N1	22	M0	N1
TCGA-35-5375	22.5	M0	N2
TCGA-95-7562	22.5	M0	N1
TCGA-69-7978	22.6	MX	N1
TCGA-55-6979	23.1	M0	N1
TCGA-MP-A4T4	23.3	M0	N1
TCGA-64-1677	23.5	M0	N2
TCGA-53-A4EZ	23.7	MX	N1
TCGA-05-4432	24.1	M0	N1
TCGA-49-4507	24.4	M0	N1
TCGA-55-1596	24.4	M0	N1
TCGA-95-A4VN	24.4	M0	N1
TCGA-50-5044	24.6	M0	N1
TCGA-97-8176	24.7	M0	N1
TCGA-05-4398	25.3	M0	N3
TCGA-73-4670	25.4	M1	N0
TCGA-62-8402	25.9	M0	N2
TCGA-55-7727	26.2	MX	N2
TCGA-50-5936	26.3	M0	N2
TCGA-50-5933	26.6	M0	N2
TCGA-62-A471	26.7	M0	N1
TCGA-50-6594	27.1	M0	N2
TCGA-86-8054	27.8	M0	N1
TCGA-86-7711	28.4	M0	N1
TCGA-78-7150	29.3	M0	N1
TCGA-05-5425	29.6	M0	N1
TCGA-93-A4JN	29.7	M1a	N0
TCGA-MP-A4TC	29.8	M0	N2
TCGA-MP-A4TI	30.2	M0	N1
TCGA-95-8494	30.8	M0	N1
TCGA-49-6742	31	M0	N1
TCGA-86-7701	31.2	M1	N0
TCGA-55-1594	32.7	M0	N2
TCGA-78-7220	34.3	M0	N2
TCGA-62-8394	34.4	M0	N2
TCGA-55-6975	34.5	M0	N1
TCGA-05-4250	36.7	M0	N1
TCGA-78-7154	36.7	M0	N2
TCGA-05-4415	36.9	M0	N2
TCGA-50-5072	37.2	M0	N2
TCGA-44-5643	38.9	M0	N2
TCGA-05-4427	40	M0	N1
TCGA-55-5899	40.1	M0	N1
TCGA-50-6591	41	M1	N0
TCGA-49-6743	41.8	MX	N2
TCGA-49-AAR3	42	MX	N1
TCGA-78-8660	42.1	M0	N1
TCGA-44-7669	42.3	MX	N1
TCGA-75-5125	45.1	M0	N1
TCGA-50-6595	46.6	M0	N2
TCGA-75-6214	46.9	M0	N2
TCGA-44-6779	49.2	MX	N1
TCGA-73-4666	53.1	M1	N0
TCGA-55-8620	58.5	M1b	N1
TCGA-78-7536	62.8	M0	N2
TCGA-44-7670	63.6	M0	N1
TCGA-05-4397	64.5	M0	N1
TCGA-91-6848	64.6	MX	N2
TCGA-55-6968	65.9	M1	N0
TCGA-78-7146	74.3	M0	N2
TCGA-53-7624	75.6	M1	N0
TCGA-44-6148	0.8	M0	N0
TCGA-67-3773	1.1	M0	N0
TCGA-78-7163	1.3	M0	N0
TCGA-49-4486	1.4	M0	N0
TCGA-50-5942	1.4	M0	N0
TCGA-35-3615	1.5	M0	N0
TCGA-50-8457	1.5	M0	N0
TCGA-75-6206	1.5	M0	N0
TCGA-78-7537	1.6	M0	N0
TCGA-97-A4M1	1.6	M0	N0
TCGA-L4-A4E6	1.7	M0	N0
TCGA-73-7498	1.8	M0	N0
TCGA-75-5146	1.9	M0	N0
TCGA-75-7025	1.9	M0	N0
TCGA-62-8397	2	M0	N0
TCGA-97-A4M2	2	M0	N0
TCGA-MP-A4TH	2	M0	N0
TCGA-97-8174	2.2	M0	N0
TCGA-67-4679	2.3	M0	N0
TCGA-55-8206	2.4	M0	N0
TCGA-73-4677	2.4	M0	N0
TCGA-44-2655	2.5	M0	N0
TCGA-67-3770	2.5	M0	N0
TCGA-38-A44F	2.6	M0	N0
TCGA-55-6980	2.6	M0	N0
TCGA-62-8395	2.6	M0	N0
TCGA-62-A46S	2.6	M0	N0
TCGA-99-AA5R	2.6	M0	N0
TCGA-S2-AA1A	2.6	M0	N0
TCGA-44-3398	2.8	M0	N0
TCGA-67-3774	2.8	M0	N0
TCGA-44-2661	2.9	M0	N0
TCGA-86-8056	2.9	M0	N0
TCGA-50-8460	3.1	M0	N0
TCGA-69-7763	3.1	M0	N0
TCGA-78-7161	3.1	M0	N0
TCGA-86-8076	3.1	M0	N0
TCGA-97-A4M3	3.1	M0	N0
TCGA-78-7539	3.2	M0	N0
TCGA-97-A4M0	3.2	M0	N0
TCGA-NJ-A55A	3.2	M0	N0
TCGA-44-6146	3.3	M0	N0
TCGA-78-7633	3.3	M0	N0
TCGA-78-7149	3.5	M0	N0
TCGA-78-7540	3.5	M0	N0
TCGA-MP-A5C7	3.5	M0	N0
TCGA-50-5935	3.7	M0	N0
TCGA-67-3772	3.7	M0	N0
TCGA-86-8668	3.7	M0	N0
TCGA-86-A456	3.7	M0	N0
TCGA-05-4403	3.9	M0	N0
TCGA-49-4501	3.9	M0	N0
TCGA-78-7162	3.9	M0	N0
TCGA-99-7458	3.9	M0	N0
TCGA-05-4249	4	M0	N0
TCGA-38-4626	4.1	M0	N0
TCGA-95-7948	4.1	M0	N0
TCGA-NJ-A4YG	4.1	M0	N0
TCGA-50-6597	4.2	M0	N0
TCGA-50-5944	4.3	M0	N0
TCGA-50-8459	4.4	M0	N0
TCGA-62-A46P	4.5	M0	N0
TCGA-55-6972	4.6	M0	N0
TCGA-97-A4M6	4.6	M0	N0
TCGA-97-8177	4.7	M0	N0
TCGA-97-A4M5	4.7	M0	N0
TCGA-05-4405	5	M0	N0
TCGA-05-4422	5.1	M0	N0
TCGA-44-7671	5.1	M0	N0
TCGA-55-6986	5.1	M0	N0
TCGA-97-8172	5.2	M0	N0
TCGA-44-2666	5.3	M0	N0
TCGA-38-7271	5.4	M0	N0
TCGA-55-A57B	5.4	M0	N0
TCGA-78-8655	5.4	M0	N0
TCGA-73-4662	5.6	M0	N0
TCGA-86-8669	5.6	M0	N0
TCGA-44-8120	6	M0	N0
TCGA-86-8280	6.1	M0	N0
TCGA-97-A4M7	6.2	M0	N0
TCGA-44-2656	6.3	M0	N0
TCGA-44-8117	6.3	M0	N0
TCGA-64-1681	6.3	M0	N0
TCGA-99-8028	6.4	M0	N0
TCGA-67-6216	6.7	M0	N0
TCGA-86-A4P7	6.7	M0	N0
TCGA-05-4426	6.8	M0	N0
TCGA-64-1676	6.8	M0	N0
TCGA-55-7281	7.1	M0	N0
TCGA-55-7574	7.5	M0	N0
TCGA-55-8090	7.6	M0	N0
TCGA-73-4658	7.7	M0	N0
TCGA-71-6725	7.8	M0	N0
TCGA-78-7153	7.9	M0	N0
TCGA-55-8616	8	M0	N0
TCGA-44-3918	8.1	M0	N0
TCGA-67-6215	8.2	M0	N0
TCGA-62-A470	8.7	M0	N0
TCGA-MN-A4N4	8.7	M0	N0
TCGA-05-5715	9.1	M0	N0
TCGA-44-4112	9.2	M0	N0
TCGA-44-A47G	9.4	M0	N0
TCGA-69-7764	9.4	M0	N0
TCGA-62-A46V	9.5	M0	N0
TCGA-78-7152	9.6	M0	N0
TCGA-05-4430	10.4	M0	N0
TCGA-97-A4LX	10.4	M0	N0
TCGA-MN-A4N5	10.5	M0	N0
TCGA-86-8073	10.8	M0	N0
TCGA-44-A47B	11.1	M0	N0
TCGA-99-8032	11.1	M0	N0
TCGA-05-4417	11.2	M0	N0
TCGA-NJ-A4YP	11.2	M0	N0
TCGA-55-6987	11.4	M0	N0
TCGA-62-A46R	11.4	M0	N0
TCGA-69-7760	11.5	M0	N0
TCGA-64-5778	11.6	M0	N0
TCGA-69-7980	11.6	M0	N0
TCGA-86-7954	11.7	M0	N0
TCGA-71-8520	11.9	M0	N0
TCGA-05-4433	12	M0	N0
TCGA-55-A48Y	12	M0	N0
TCGA-MP-A4TJ	12	M0	N0
TCGA-78-8648	12.2	M0	N0
TCGA-55-8203	12.5	M0	N0
TCGA-97-8179	12.5	M0	N0
TCGA-97-8175	12.8	M0	N0
TCGA-NJ-A4YF	12.9	M0	N0
TCGA-NJ-A4YQ	13	M0	N0
TCGA-62-A472	13.1	M0	N0
TCGA-80-5608	13.2	M0	N0
TCGA-L4-A4E5	13.2	M0	N0
TCGA-50-5049	13.4	M0	N0
TCGA-50-5066	14.1	M0	N0
TCGA-50-6673	14.2	M0	N0
TCGA-75-5147	15.2	M0	N0
TCGA-91-6828	15.2	M0	N0
TCGA-50-7109	15.3	M0	N0
TCGA-MP-A4TF	15.4	M0	N0
TCGA-44-6145	15.7	M0	N0
TCGA-4B-A93V	15.8	M0	N0
TCGA-35-4123	15.9	M0	N0
TCGA-86-8075	15.9	M0	N0
TCGA-05-4389	16.5	M0	N0
TCGA-55-1592	16.6	M0	N0
TCGA-05-4382	16.7	M0	N0
TCGA-35-4122	16.7	M0	N0
TCGA-64-5781	16.7	M0	N0
TCGA-91-6835	16.7	M0	N0
TCGA-44-A4SS	16.8	M0	N0
TCGA-86-8672	16.9	M0	N0
TCGA-50-5939	17.8	M0	N0
TCGA-55-8085	17.9	M0	N0
TCGA-44-3919	18	M0	N0
TCGA-69-A59K	18.2	M0	N0
TCGA-86-7713	18.5	M0	N0
TCGA-78-8662	18.7	M0	N0
TCGA-44-7672	19.6	M0	N0
TCGA-95-7944	19.8	M0	N0
TCGA-64-1678	20.2	M0	N0
TCGA-78-7535	20.2	M0	N0
TCGA-53-7813	20.3	M0	N0
TCGA-55-8208	20.7	M0	N0
TCGA-86-7953	20.8	M0	N0
TCGA-67-3771	21.4	M0	N0
TCGA-55-7910	21.6	M0	N0
TCGA-86-A4JF	21.9	M0	N0
TCGA-73-7499	22.9	M0	N0
TCGA-38-4629	23.1	M0	N0
TCGA-05-4390	23.5	M0	N0
TCGA-44-3917	24.1	M0	N0
TCGA-05-4420	24.2	M0	N0
TCGA-86-8585	25	M0	N0
TCGA-55-7576	25.8	M0	N0
TCGA-44-8119	27	M0	N0
TCGA-91-6840	28	M0	N0
TCGA-69-7973	28.3	M0	N0
TCGA-95-7947	28.3	M0	N0
TCGA-78-7143	28.5	M0	N0
TCGA-69-8255	29	M0	N0
TCGA-75-7027	29	M0	N0
TCGA-44-2662	30	M0	N0
TCGA-MP-A4SV	30.2	M0	N0
TCGA-49-4514	31	M0	N0
TCGA-55-8089	31.4	M0	N0
TCGA-86-8673	31.9	M0	N0
TCGA-44-7661	34	M0	N0
TCGA-62-A46O	35.8	M0	N0
TCGA-86-7955	36.1	M0	N0
TCGA-64-5775	36.3	M0	N0
TCGA-86-A4D0	36.4	M0	N0
TCGA-50-5931	37	M0	N0
TCGA-38-4631	37.5	M0	N0
TCGA-MP-A4TA	37.7	M0	N0
TCGA-50-6592	39.9	M0	N0
TCGA-80-5611	40.8	M0	N0
TCGA-64-5774	43.9	M0	N0
TCGA-05-4424	47.4	M0	N0
TCGA-73-A9RS	49.3	M0	N0
TCGA-55-8205	52.2	M0	N0
TCGA-78-7542	52.4	M0	N0

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TPX2 Promotes Metastasis and Serves as a Marker of Poor Prognosis in Non-Small Cell Lung Cancer

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