15 July 2020: Clinical Research
Argatroban Increased the Basal Vein Drainage and Improved Outcomes in Acute Paraventricular Ischemic Stroke Patients
Shoufeng Liu 12AE* , Peipei Liu 2BCDEF* , Po Wang 3BC , Fang Zhang 4BD , Lijun Wang 5BD , Yu Wang 6BD , Hao Lu 7B , Xiaofeng Ma 4AG*DOI: 10.12659/MSM.924593
Med Sci Monit 2020; 26:e924593
Table 1 Characteristics of the patients at baseline.
| Characteristic | Control n=30 | Argatroban n=30 | p value |
|---|---|---|---|
| Age, y | 57.1±10.7 | 57.7±8.8 | 0.33 |
| Female sex, n (%) | 6 (20) | 7 (23) | 0.75 |
| Previous stroke, n (%) | 3 (10) | 2 (6) | 0.64 |
| Risk factors, n (%) | |||
| Hypertension | 17 (57) | 19 (63) | 0.60 |
| Heart disease | 2 (6) | 3 (10) | 0.64 |
| Hyperlipidemia | 5 (17) | 7 (23) | 0.52 |
| Smoking | 11 (37) | 13 (43) | 0.60 |
| Renal failure | 0 (0) | 0 (0) | 1.00 |
| Diabetes mellitus | 0 (0) | 0 (0) | 1.00 |
| Etiology*, n (%) | |||
| Subtype 1: atheromatosis | 30 (100) | 30 (100) | 1.00 |
| Subtype 2: embolus | 0 (0) | 0 (0) | 1.00 |
| Subtype 3: lacunar infarct | 0 (0) | 0 (0) | 1.00 |
| Subtype 4: other causes | 0 (0) | 0 (0) | 1.00 |
| Subtype 5: undetermined | 0 (0) | 0 (0) | 1.00 |
| INR | 1.0±0.1 | 1.0±0.1 | 0.69 |
| Infarct volume on admission, mL | 21.1±2.9 | 20.7±3.1 | 0.85 |
| NIHSS score at baseline, median(range) | 8 (5~12) | 8 (5~13) | 0.58 |
| Time to treatment, h | 26±8 | 25±10 | 0.36 |
| Plus-minus values are mean±SE. a Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. INR – international normalized ratio; NIHSS – National Institutes of Health Stroke Scale. | |||