15 July 2020: Clinical Research
Association Between Ghrelin Gene Polymorphism and Cerebral Infarction
Li Chen 1ABE , Hua Zhao 1BCF , Jing Shen 2DF , Xiaoyu Ji 3ACG*DOI: 10.12659/MSM.924539
Med Sci Monit 2020; 26:e924539
Table 4 Haplotype analysis of ghrelin gene loci rs26312, rs26802, and rs27647.
| Haplotype | Control group | Disease group | OR | 95%CI | χ2 | P |
|---|---|---|---|---|---|---|
| AGC | 39.18 (0.098) | 77.26 (0.193) | 2.205 | 1.459–3.331 | 14.574 | 0.000 |
| AGT | 40.99 (0.102) | 47.23 (0.118) | 1.173 | 0.753–1.827 | 0.497 | 0.481 |
| ATC | 58.91 (0.147) | 26.32 (0.066) | 0.408 | 0.252–0.661 | 13.952 | 0.000 |
| ATT | 49.92 (0.125) | 56.20 (0.140) | 1.146 | 0.761–1.726 | 0.428 | 0.513 |
| GGC | 54.46 (0.136) | 36.83 (0.092) | 0.643 | 0.413–1.002 | 3.843 | 0.050 |
| GGT | 52.38 (0.131) | 60.69 (0.152) | 1.187 | 0.797–1.769 | 0.711 | 0.399 |
| GTC | 52.45 (0.131) | 65.60 (0.164) | 1.3 | 0.878–1.925 | 1.717 | 0.190 |
| GTT | 51.71 (0.129) | 29.89 (0.075) | 0.544 | 0.339–0.873 | 6.501 | 0.011 |