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17 August 2020: Clinical Research

Evaluation of Ovarian Tumors with Multidetector Computed Tomography and Tumor Markers: Differentiation of Stage I Serous Borderline Tumors and Stage I Serous Malignant Tumors Presenting as Solid-Cystic Mass

Xin-Ping Yu 1BCE , Ying Liu 2C , Jin-Wen Jiao 1D , Hong-Juan Yang 1B , Rui-Jing Wang 1D , Shuai Zhang 3ACF*

DOI: 10.12659/MSM.924497

Med Sci Monit 2020; 26:e924497

Table 3 Comparison of quantitative measures of SBOTs and SMOTs.

ParameterSBOTs (n=48)SMOTs (n=54)P value
CA125 (U/mL)130.3 (40.1–326.1)328.8 (66.5–1270.5)0.005
CA19-9 (U/mL)15.9 (10.4–24.9)18.3 (9.0–41.9)0.573
CEA (ng/mL)1.2 (0.5–1.8)1.4 (0.9–2.3)0.059
HE4 (pmol/L)74.6 (64.1–95.1)123.3 (73.4–255.8)
Arterial phases attenuation value (Hu)54.5 (48.1–59.2)53.6 (46.8–56.8)0.163
Venous phases attenuation value (Hu)60.1 (56.6–65.6)57.5 (55.0–64.9)0.056
Equilibrium phase attenuation value (Hu)66.5 (61.5–73.5)68.4 (59.4–68.9)0.062
Size (mm)79.1 (56.8–109.4)80.9 (60.8–112.6)0.580
Maximum thickness of wall (mm)2.6 (1.8–3.6)3.45 (2.8–3.8)0.001
Maximum thickness of septa (mm)2.6 (2.3–3.6)3.5 (2.8–3.9)0.002
Maximum diameter of solid component (mm)31.5 (25.4–39.8)43.5 (31.6–51.0)
Data are presented as the median (inter-quartile range). SBOTs – serous borderline ovarian tumors; SMOTs – serous malignant ovarian tumors; CA125 – serum cancer antigen 125; CA19-9 – carbohydrate antigen 19-9; CEA – carcinoembryonic antigen; HE4 – human epididymis protein 4.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750