30 July 2020>: Clinical Research
Fiber Type-Specific Morphological and Cellular Changes of Paraspinal Muscles in Patients with Severe Adolescent Idiopathic Scoliosis
Xiexiang Shao 1ABCEF* , Jian Chen 1ABCF* , Jingfan Yang 1ADFG* , Wenyuan Sui 1BDFG , Yaolong Deng 1BCEF , Zifang Huang 2BCE , Ping Hu 3ACEG* , Junlin Yang 1ABCDEG*DOI: 10.12659/MSM.924415
Med Sci Monit 2020; 26:e924415
Table 4 Correlation analysis between clinical parameters and the bilateral differences of fiber type specific morphological/cellular characteristics.
Age at initiation | Cobb angle | AVT | CB | |||||
---|---|---|---|---|---|---|---|---|
r | P value | r | P value | r | P value | r | P value | |
Difference of type I numerical proportion | −0.120 | 0.711 | −0.002 | 0.996 | −0.494 | 0.103 | −0.167 | 0.603 |
Difference of type I area proportion | −0.198 | 0.537 | −0.061 | 0.850 | −0.182 | 0.571 | 0.091 | 0.779 |
Ratio of CSA | ||||||||
Type I | 0.004 | 0.991 | * | 0.497 | 0.100 | 0.040 | 0.901 | |
Type II | −0.172 | 0.593 | * | 0.322 | 0.307 | −0.269 | 0.398 | |
Total | 0.007 | 0.982 | * | 0.438 | 0.155 | −0.180 | 0.576 | |
Difference of myonuclei density | ||||||||
Type I | −0.071 | 0.826 | 0.302 | 0.341 | * | −0.150 | 0.641 | |
Type II | 0.108 | 0.737 | −0.175 | 0.587 | −0.133 | 0.680 | −0.329 | 0.297 |
Total | 0.093 | 0.773 | 0.326 | 0.301 | 0.571 | 0.053 | −0.349 | 0.266 |
Difference of total SC density | ||||||||
Type I | −0.228 | 0.476 | 0.351 | 0.263 | * | 0.465 | 0.127 | |
Type II | 0.150 | 0.643 | 0.266 | 0.403 | * | 0.088 | 0.787 | |
Total | −0.019 | 0.954 | 0.346 | 0.271 | 0.539 | 0.070 | 0.328 | 0.297 |
Difference of activated SC density | ||||||||
Type I | −0.116 | 0.720 | 0.495 | 0.102 | * | 0.053 | 0.870 | |
Type II | 0.225 | 0.482 | 0.269 | 0.399 | −0.025 | 0.940 | −0.523 | 0.081 |
Total | −0.064 | 0.844 | 0.575 | 0.050 | 0.392 | 0.207 | −0.427 | 0.166 |
AVT – apical vertebrae translation; CB – coronal balance; CSA – cross sectional area; SC – satellite cell. * Significant if value |