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04 September 2020: Animal Study

Individualized Running Wheel System with a Dynamically Adjustable Exercise Area and Speed for Rats Following Ischemic Stroke

Yu-Lin Wang 123ABC , Jui-Chi Cheng 4AB , Ching-Ping Chang 5BCDE , Fong-Chin Su 1EF* , Chi-Chun Chen 4ABDEFG*

DOI: 10.12659/MSM.924411

Med Sci Monit 2020; 26:e924411

Table 2 Serum cortisol levels.

Time pointsSham (n=6)Control (n=8)Treadmill (n=8)MRW (n=8)DEARW (n=8)
Pre-surgery0.03±0.080.02±0.040.05±0.030.04±0.030.03±0.05
Day 14 post-surgery0.02±0.040.03±0.050.52±0.17* 0.05±0.08# 0.07±0.08#
Day 21 post-surgery0.06±0.030.12±0.040.37±0.14* 0.33±0.10* 0.05±0.08#
Day 28 post-surgery0.04±0.050.13±0.050.52±0.31* 0.13±0.12# 0.08±0.04#
Values are means±S.D. Sham – sham operation; Control – MCAO without rehabilitation; Treadmill – MCAO with treadmill rehabilitation; MRW – MCAO with motorized running wheel (MRW) rehabilitation; DEARW – MCAO with dynamic exercise area running wheel (DEARW) rehabilitation.
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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750