Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

22 July 2020: Clinical Research

Phospholipase Cɛ Regulates Prostate Cancer Lipid Metabolism and Proliferation by Targeting AMP-Activated Protein Kinase (AMPK)/Sterol Regulatory Element-Binding Protein 1 (SREBP-1) Signaling Pathway

Yongbo Zheng 1ABCDEF* , Jiajia Jin 2ABCDF* , Yingying Gao 3ACF , Chunli Luo 4AG , Xiaohou Wu 1AG* , Jiayu Liu 1ABCDE*

DOI: 10.12659/MSM.924328

Med Sci Monit 2020; 26:e924328

Table 1 Demographic and clinical characteristics of patients.

CharacteristicsOverallPLCɛ
Positive (%)Negative (%)
Prostate cancer6041 (68.3%)19 (31.7%)
Age of patients with PCa (years)
 Median646563–68P=0.165*
 Quartiles 25–7562–6863–6961
Histological stage
 Ta–T116610**
 T2–T444359
Gleason score
21129P=0.787**
 ≥7392415
PSA of patients with PCa (μg/l)
 Median177178155P=0.546*
 Quartiles 25–7552.1–49065.7–283.541.6–491.6
Metastases in PCa
 Bone23203**
 Visceral20182**
* Mann-Whitney test;
** Chi-square statistical significance numbers indicated in bold font.
PSA – prostate-specific antigen.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750