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23 June 2020: Database Analysis

Bioinformatics-Based Study to Investigate Potential Differentially Expressed Genes and miRNAs in Pediatric Sepsis

Kexin Xie 1BE* , Shan Kong 1CE* , Fuxing Li 1DF , Yulin Zhang 1CD , Jing Wang 2DF , Weidong Zhao 1AG*

DOI: 10.12659/MSM.923881

Med Sci Monit 2020; 26:e923881

Supplementary Table 2 GO molecular function terms for DEGs between the control and pediatric sepsis groups.

IndexNameP-valueAdjusted P-valueOdds ratioCombined score
1Complement receptor activity (GO: 0004875)0.0000045050.00518632.91405.11
2Phosphofructokinase activity (GO: 0008443)0.0024610.314725.86155.33
3Interleukin-1 receptor binding (GO: 0005149)0.00054900.158018.10135.88
4C-C chemokine binding (GO: 0019957)0.0032570.312422.62129.57
5UDP-glucosyltransferase activity (GO: 0035251)0.0041580.319020.11110.26
6Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO: 0016813)0.0051590.349318.1095.33
7Protein kinase C activity (GO: 0004697)0.0051590.371218.1095.33
8Metalloendopeptidase inhibitor activity (GO: 0008191)0.0074580.451815.0873.88
9Cysteine-type endopeptidase inhibitor activity (GO: 0004869)0.00024460.093838.8773.78
10Cysteine-type endopeptidase inhibitor activity involved in apoptotic process (GO: 0043027)0.0022700.326511.3168.87

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750