Circ_cse1l Inhibits Colorectal Cancer Proliferation by Binding to eIF4A3

28 August 2020: Clinical Research

Bin Xu ^1ABCDEF , Ning Yang ^1BCDF , Yabin Liu ^1BCDF , Peng Kong ^2ACE , Mei Han ^2AG , Binghui Li ^1ABCDEFG*

DOI: 10.12659/MSM.923876

Med Sci Monit 2020; 26:e923876

Table 1 Correlation between the expression of circ_cse1l and the clinicopathology of colorectal cancer patients.

Clinical parameter	Group	No. of patients	Mean±S.E.	t-value	P-value
Gender	Male	27	5.033±2.190	0.74	0.466
Gender	Female	23	5.582±2.952	0.74	0.466
Age (years)	≤60	19	5.047±2.381	0.51	0.611
Age (years)	>60	31	5.432±2.685	0.51	0.611
Tumor size (cm)	≤5	33	5.136±2.783	0.57	0.571
Tumor size (cm)	>5	17	5.576±2.094	0.57	0.571
Histology/differentiation	Well+Moderate	41	5.363±2.637	0.45	0.652
Histology/differentiation	Poor	9	4.933±2.252	0.45	0.652
Depth of invasion	T1+T2	11	3.581±2.046	2.65	0.011^*
Depth of invasion	T3+T4	39	5.766±2.343	2.65	0.011^*
Lymph node metastasis	Negative	35	5.485±2.797	0.98	0.332
Lymph node metastasis	Positive	15	4.821±1.881	0.98	0.332
Tumor stage	I–II	34	5.601±2.755	1.43	0.161
Tumor stage	III–IV	16	4.618±1.988	1.43	0.161
Tumor location	Colon	23	4.826±2.357	1.19	0.239
Tumor location	Rectum	27	5.677±2.696	1.19	0.239
^* P