16 June 2020>: Clinical Research
Lower Platelet Aggregation Is a Risk Factor for Dual Antiplatelet Therapy-Associated Bleeding: A Preliminary Retrospective Study with Genotype Analysis
Dongdong Yuan 1ABCD , Xiangfen Shi 2BCD , Liping Guo 1BF , Gaobiao Wang 1BF , Yujie Zhao 1B , Yuling Yang 1B , Hanjuan Zhang 1B , Qiong Huang 1B , Yiqiang Yuan 1AE*DOI: 10.12659/MSM.923758
Med Sci Monit 2020; 26:e923758
Table 2 Comparison of the platelet aggregation rates of the patients with bleeding events and those without bleeding events.
Bleeding patients (n=25) | Non-bleeding patients (n=25) | P | |
---|---|---|---|
ACA-induced platelet aggregation (%) | 13.28±8.46 | 24.93±9.89 | |
ADP-induced platelet aggregation (%) | 16.17±9.74 | 16.88±12.69 | 0.829 |
ACA+ADP-induced platelet aggregation (%) | 30.70±17.79 | 47.28±14.84 | 0.003 |
ACA – arachidonic acid; ADP – adenosine diphosphate. |