29 June 2020>: Animal Study
Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model
Hai-Yan Fu 1EF , Wei-Min Bao 2C , Cai-Xia Yang 1D , Wei-Ju Lai 1D , Jia-Min Xu 1B , Hai-Yan Yu 1B , Yi-Na Yang 1B , Xu Tan 1B , Ajay Kumar Gupta 1F , Ying-Mei Tang 1AG*DOI: 10.12659/MSM.923726
Med Sci Monit 2020; 26:e923726
Supplementary Table 8 The amount of IL-12 secreted by each culture system (unit: pg/mL).
PBC | Mean | Std | CON | Mean | Std | t | P |
---|---|---|---|---|---|---|---|
K1 | 8.045 | 0.419 | K2 | 7.003 | 1.256 | 1.7597 | 0.1165 |
N1 | 1.202 | 0.1124 | N2 | 3.164 | 0.1778 | −20.8566 | |
K1+N2 | 12.778 | 1.391 | K2+N1 | 5.9485 | 0.499 | 10.3333 | |
K1+L1 | 2.9695 | 0.311 | K2+L1 | 1.612 | 0.0683 | 9.5331 | |
K1+L10 | 218.852 | 18.55 | K2+L10 | 123.282 | 9.74 | 10.1997 | |
K1+N2+L1 | 263.9345 | 12.79 | K2+N1+L1 | 253.4485 | 33.9 | 0.6471 | 0.5357 |
K1+N2+L1/T | 22.7775 | 2.27 | K2+N1+L1/T | 3.2215 | 0.408 | 18.9599 | |
K1+N2+L10 | 2218.3217 | 27.5 | K2+N1+L10 | 428.737 | 33.5 | 92.3276 | |
K1+N2+L10/T | 461.027 | 50.2 | K2+N1+L10/T | 47.928 | 3.42 | 18.3582 | |
1 indicates the cells are derived from the PBC group, 2 indicates the cells are derived from the CON group. IL – interleukin; PBC – primary biliary cholangitis; CON – control. |