29 June 2020: Animal Study
Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model
Hai-Yan Fu 1EF , Wei-Min Bao 2C , Cai-Xia Yang 1D , Wei-Ju Lai 1D , Jia-Min Xu 1B , Hai-Yan Yu 1B , Yi-Na Yang 1B , Xu Tan 1B , Ajay Kumar Gupta 1F , Ying-Mei Tang 1AG*DOI: 10.12659/MSM.923726
Med Sci Monit 2020; 26:e923726
Supplementary Table 7 The amount of IL-10 secreted by each culture system (unit: pg/mL).
| PBC | Mean | Std | CON | Mean | Std | t | P |
|---|---|---|---|---|---|---|---|
| K1 | 71.78 | 7.43 | K2 | 58.11 | 5.12 | 3.3876 | 0.0095 |
| N1 | 47.29 | 2.40 | N2 | 63.70 | 6.27 | −5.4656 | 0.0006 |
| K1+N2 | 64.61 | 6.95 | K2+N1 | 53.76 | 2.5 | 3.2848 | 0.0111 |
| K1+L1 | 58.39 | 6.76 | K2+L1 | 68.93 | 7.17 | −2.3917 | 0.0437 |
| K1+L10 | 53.79 | 5.07 | K2+L10 | 66.43 | 6.41 | −3.4583 | 0.0086 |
| K1+N2+L1 | 58.59 | 2.64 | K2+N1+L1 | 62.83 | 3.07 | −2.3415 | 0.0473 |
| K1+N2+L1/T | 52.20 | 2.47 | K2+N1+L1/T | 60.23 | 4.11 | −3.7446 | 0.0057 |
| K1+N2+L10 | 63.00 | 3.30 | K2+N1+L10 | 67.30 | 8.13 | −1.0958 | 0.305 |
| K1+N2+L10/T | 54.03 | 5.99 | K2+N1+L10/T | 60.69 | 6.76 | −1.6488 | 0.1378 |
| 1 indicates the cells are derived from the PBC group, 2 indicates the cells are derived from the CON group. IL – interleukin; PBC – primary biliary cholangitis; CON – control. | |||||||