29 June 2020>: Animal Study
Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model
Hai-Yan Fu 1EF , Wei-Min Bao 2C , Cai-Xia Yang 1D , Wei-Ju Lai 1D , Jia-Min Xu 1B , Hai-Yan Yu 1B , Yi-Na Yang 1B , Xu Tan 1B , Ajay Kumar Gupta 1F , Ying-Mei Tang 1AG*DOI: 10.12659/MSM.923726
Med Sci Monit 2020; 26:e923726
Supplementary Table 2 Expression of RAE-1 and F4/80 after stimulation of Kupffer with different concentrations of LPS.
Group | KCs | KCs+LPS1 | KCs+LPS10 | F | P | |
---|---|---|---|---|---|---|
RAE-1 | PBC | 26.89±2.26 | 42.05±6.03 | 51.23±4.17 | 61.6088 | |
CON | 17.67±1.77 | 19.09±1.68 | 27.65±3.40 | 39.9400 | ||
9.0845 | 10.3745 | 12.3957 | ||||
F4/80 | PBC | 42.68±4.26 | 63.52±4.85 | 65.49±6.05 | 48.9818 | |
CON | 34.88±4.81 | 46.18±2.41 | 50.99±7.68 | 18.6682 | ||
3.43360 | 9.05594 | 4.19487 | ||||
0.002 | 0.0004 | |||||
RAE-1 – retinoic acid early inducible-1; LPS – lipopolysaccharide; PBC – primary biliary cholangitis; CON – control. |