29 June 2020>: Animal Study
Kupffer Cells Regulate Natural Killer Cells Via the NK group 2, Member D (NKG2D)/Retinoic Acid Early Inducible-1 (RAE-1) Interaction and Cytokines in a Primary Biliary Cholangitis Mouse Model
Hai-Yan Fu 1EF , Wei-Min Bao 2C , Cai-Xia Yang 1D , Wei-Ju Lai 1D , Jia-Min Xu 1B , Hai-Yan Yu 1B , Yi-Na Yang 1B , Xu Tan 1B , Ajay Kumar Gupta 1F , Ying-Mei Tang 1AG*DOI: 10.12659/MSM.923726
Med Sci Monit 2020; 26:e923726
Supplementary Table 10 The amount of IFN-γ secreted by each culture system (unit: pg/mL).
PBC | Mean | Std | CON | Mean | Std | t | P |
---|---|---|---|---|---|---|---|
K1 | 16.80 | 1.631 | K2 | 3.64 | 0.397 | 17.5303 | |
N1 | 41.28 | 5.39 | N2 | 13.94 | 1.22 | 11.0623 | |
K1+N2 | 315.35 | 31.8 | K2+N1 | 545.89 | 89.8 | −5.4113 | 0.0006 |
K1+L1 | 9.33 | 0.721 | K2+L1 | 3.47 | 0.606 | 13.9124 | |
K1+L10 | 3.83 | 0.526 | K2+L10 | 6.27 | 0.357 | −8.5826 | |
K1+N2+L1 | 1818.07 | 143 | K2+N1+L1 | 1928.78 | 137.4 | −1.2483 | 0.2472 |
K1+N2+L1/T | 66.35 | 5.29 | K2+N1+L1/T | 132.94 | 13.05 | −10.5742 | |
K1+N2+L10 | 1906.59 | 118.8 | K2+N1+L10 | 2846.04 | 186.6 | −9.4964 | |
K1+N2+L10/T | 768.80 | 79.9 | K2+N1+L10/T | 1077.30 | 53.4 | −7.1781 | 0.0001 |
1 indicates the cells are derived from the PBC group, 2 indicates the cells are derived from the CON group. IFN-γ – interferon-γ; PBC – primary biliary cholangitis; CON – control. |