25 June 2020>: Database Analysis
Effects of Marital Status on Prognosis in Women with Infiltrating Ductal Carcinoma of the Breast: A Real-World 1: 1 Propensity-Matched Study
Tian Lan 1ABCDEF** , Yunyan Lu 2BCD* , Hua Luo 1CD , Junling He 1BE , Jiawei He 1CF , Zujian Hu 1EF , Haibin Xu 1A*DOI: 10.12659/MSM.923630
Med Sci Monit 2020; 26:e923630
Table 3 Impact of marital status on the BCSS by univariate and multivariate survival analysis before PSM.
Characteristics | 5-year OS | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|---|
Log rank χ2 | P value | HR | 95% CI | P value | ||
Marital status | 1200.1 | |||||
Married | 92.9% | Reference | ||||
Divorced | 90.2% | 1.15 | 1.09–1.21 | |||
Single | 87.6% | 1.27 | 1.21–1.33 | |||
Widowed | 86.4% | 1.32 | 1.25–1.40 | |||
Age | 1228.9 | |||||
18–49 | 90.6% | Reference | ||||
50–59 | 91.4% | 2.04 | 1.93–2.15 | |||
60–69 | 92.9% | 1.34 | 1.29–1.40 | |||
70–79 | 91.0% | 1.08 | 1.03–1.12 | |||
≥80 | 82.7% | 0.96 | 0.92–1.00 | 0.040 | ||
Race | 1194.6 | |||||
White | 91.6% | Reference | ||||
Black | 83.8% | 1.27 | 1.21–1.33 | |||
API | 93.6% | 0.8 | 0.74–0.86 | |||
AI | 89.5% | 1.27 | 1.03–1.57 | 0.026 | ||
Gender | 23.2 | |||||
Male | 86.5% | Reference | ||||
Female | 90.9% | 0.88 | 0.74–1.05 | 0.145 | ||
Median household income | 468.0 | |||||
Quartile 1 | 88.7% | Reference | ||||
Quartile 2 | 90.3% | 0.80 | 0.77–0.84 | |||
Quartile 3 | 91.8% | 1.00 | 0.97–1.04 | 0.846 | ||
Quartile 4 | 93.0% | 1.04 | 1.00–1.07 | 0.067 | ||
Insurance | 304.8 | |||||
Uninsured | 81.3% | Reference | ||||
Insured | 91.1% | 0.74 | 0.67–0.81 | |||
Grade | 5565.4 | |||||
I | 98.2% | Reference | ||||
II | 93.7% | 2.01 | 1.82–2.22 | |||
III | 83.9% | 3.71 | 3.36–4.10 | |||
Stage | 38639.6 | |||||
I | 97.9% | Reference | ||||
II | 91.2% | 2.93 | 2.74–3.12 | |||
III | 75.2% | 8.98 | 8.37–9.63 | |||
IV | 35.7% | 24.52 | 22.72–26.47 | |||
Subtype | 4705.1 | |||||
HR−/HER2− (triple negative) | 79.1% | Reference | ||||
HR−/HER2+ (HER2 enriched) | 85.6% | 0.43 | 0.40–0.47 | |||
HR+/HER2− (Luminal A) | 93.5% | 0.41 | 0.39–0.43 | |||
HR+/HER2+ (Luminal B) | 90.9% | 0.32 | 0.30–0.34 | |||
Surgery | 19591.4 | |||||
No surgery | 51.9% | Reference | ||||
BCS | 95.7% | 0.33 | 0.31–0.36 | |||
Mastectomy | 88.7% | 0.45 | 0.42–0.47 | |||
Radiation | 922.3 | |||||
None/unknown | 88.5% | Reference | ||||
Yes | 92.8% | 0.86 | 0.82–0.89 | |||
Chemotherapy | 1605.0 | |||||
No/unknown | 94.0% | Reference | ||||
Yes | 87.3% | 0.85 | 0.82–0.90 | |||
BCSS – breast cancer-specific survival; PSM – propensity score matching; HR – hazard ratio; CI – confidence interval. |