28 September 2020>: Clinical Research
Catechol-O-Methyltransferase Gene Polymorphisms and the Risk of Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Patients with Varying Tumor Hormonal Receptor Expression
Wen Li 1ABCE , Jingjing Zhao 2B , Ke Ding 2B , Herta H. Chao 3E , Chiang-Shan R. Li 4BC , Huaidong Cheng 2AG* , Li Shen 5AG*DOI: 10.12659/MSM.923567
Med Sci Monit 2020; 26:e923567
Table 2 Neuropsychological performance before and after chemotherapy.
Task | Mean±SD | |
---|---|---|
Before chemotherapy (n=232) | After chemotherapy (n=232) | |
MMSE | 27.27±1.57 | 26.65±1.64* |
DST | 6.19±0.73 | 5.95±0.97** |
VFT | 11.48±1.52 | 9.96±2.13** |
EBPM | 2.72±1.01 | 2.00±1.19** |
TBPM | 4.98 ± 0.97 | 4.75 ±0.91* |
* ** MMSE – Mini-Mental State Examination; DST – digit span test; VFT – verbal fluency test; EBPM – event-based prospective memory task; TBPM – time-based prospective memory task. |