07 November 2020: Clinical Research
Effect of Red Blood Cell Storage Duration on Outcomes of Isolated Traumatic Brain Injury
Kun Xiao 1AE* , Fei Zhao 2AE* , Qiang Liu 3B , Jinliang Jiang 4B , Zhiyong Chen 5C , Wei Gong 6D , Zengwang Zheng 7F , Aiping Le 1A*DOI: 10.12659/MSM.923448
Med Sci Monit 2020; 26:e923448
Table 3 Univariate regression analysis of 90-day mortality in patients with iTBI.
| Variables | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|
| P | OR | 95% CI | P | OR | 95% CI | |||
| Lower | Upper | Lower | Upper | |||||
| Age | 0.001 | 1.020 | 1.008 | 1.033 | 0.010 | 1.026 | 1.006 | 1.045 |
| Gender (Male) | 0.085 | 0.755 | 0.549 | 1.040 | 0.002 | 0.513 | 0.335 | 0.785 |
| Weight | 0.020 | 0.983 | 0.969 | 0.997 | 0.155 | 0.985 | 0.965 | 1.006 |
| Fresh blood | 0.262 | 1.192 | 0.877 | 1.620 | 0.231 | 1.252 | 0.867 | 1.808 |
| Diabetes history | 0.377 | 0.769 | 0.430 | 1.378 | 0.192 | 0.591 | 0.268 | 1.302 |
| Hypertension history | 2.031 | 1.377 | 2.997 | 0.193 | 1.543 | 0.803 | 2.965 | |
| GCS score on admission | 0.512 | 0.981 | 0.927 | 1.039 | 0.751 | 1.011 | 0.944 | 1.083 |
| Head and neck AIS | 0.801 | 1.025 | 0.846 | 1.242 | 0.739 | 1.039 | 0.831 | 1.298 |
| ISS score | 0.163 | 0.987 | 0.969 | 1.005 | 0.858 | 1.002 | 0.980 | 1.025 |
| LOS in hospital | 1.197 | 1.163 | 1.233 | 1.178 | 1.142 | 1.215 | ||
| LOS in ICU | 0.161 | 0.766 | 0.527 | 1.112 | 0.984 | 0.990 | 0.387 | 2.536 |
| Mechanical ventilation | 0.125 | 1.029 | 0.992 | 1.068 | 0.555 | 1.028 | 0.937 | 1.129 |
| Brain injury | ||||||||
| Subdural hematoma | Ref | Ref | ||||||
| Epidural hematoma | 0.652 | 0.925 | 0.657 | 1.300 | 0.604 | 1.181 | 0.630 | 2.212 |
| Subarachnoid hemorrhage | 0.286 | 0.156 | 0.524 | 0.005 | 0.332 | 0.153 | 0.722 | |
| Intracerebral hemorrhage | 0.996 | 0.000 | 0.000 | – | 0.996 | 0.000 | 0.000 | – |
| Intraventricular hemorrhage | 0.039 | 2.053 | 1.037 | 4.063 | 0.017 | 3.027 | 1.219 | 7.515 |
| Brain contusion | 0.998 | 0.000 | 0.000 | – | 0.998 | 0.000 | 0.000 | – |
| Diffuse axonal injury | 0.331 | 0.360 | 0.046 | 2.821 | 0.325 | 0.258 | 0.017 | 3.838 |
| Causes of injury | ||||||||
| Non-accidental injury | Ref | Ref | ||||||
| Fall over injury | 0.485 | 1.137 | 0.793 | 1.632 | 0.500 | 0.806 | 0.432 | 1.506 |
| Traffic injury | 0.035 | 0.563 | 0.330 | 0.959 | 0.253 | 1.500 | 0.748 | 3.006 |
| High falling injury | 0.255 | 0.774 | 0.498 | 1.203 | 0.036 | 0.528 | 0.291 | 0.958 |
| iTBI – isolated traumatic brain injury; OR – odds ratio; CI – confidence interval; RBCs – red blood cells; GCS – Glasgow coma scale; AIS – abbreviated injury scale; ISS – injury severity score; LOS – the length of stay; ICU – Intensive Care Unit. | ||||||||