Effect of Red Blood Cell Storage Duration on Outcomes of Isolated Traumatic Brain Injury

07 November 2020: Clinical Research

Kun Xiao ^1AE* , Fei Zhao ^2AE* , Qiang Liu ^3B , Jinliang Jiang ^4B , Zhiyong Chen ^5C , Wei Gong ^6D , Zengwang Zheng ^7F , Aiping Le ^1A*

DOI: 10.12659/MSM.923448

Med Sci Monit 2020; 26:e923448

Table 1 Characteristics of the iTBI patients.

Variables	Fresh RBCs (n=523)	Old RBCs (n=729)	t/χ2	P
Age, years, mean ±SD	43.34±11.96	42.11±12.98	1.730	0.084
Gender, Male, n (%)	375 (71.7)	489 (67.1)	3.044	0.081
Weight, Kg, mean±SD	61.49±10.58	62.50±10.86	−1.647	0.100
Blood storage duration, mean±SD	12.08±1.46	24.28±2.69	−102.904
Diabetes history, n (%)	46 (8.8)	64 (8.8)		0.992
Hypertension history, n (%)	70 (13.4)	97 (13.3)	0.002	0.968
GCS score on admission, mean±SD	10.72±2.67	10.58±2.63	0.916	0.360
Head and neck AIS, mean±SD	4.03±0.80	4.03±0.79	0.009	0.993
ISS score, mean±SD	18.40±7.91	18.78±8.50	−0.810	0.418
LOS in hospital, days, mean±SD	19.03±6.23	19.45±6.18	−1.183	0.237
LOS in ICU, days, mean±SD	1.75±0.21	1.76±0.18	0.904	0.336
Mechanical ventilation, days, mean±SD	1.65±0.15	1.68±0.51	−1.37	0.172
Brain injury, n (%)			10.662	0.099
Subdural hematoma	187 (35.8)	294 (40.3)
Epidural hematoma	154 (29.4)	221 (30.3)
Subarachnoid hemorrhage	97 (18.5)	96 (13.2)
Intracerebral hemorrhage	48 (9.2)	63 (8.6)
Intraventricular hemorrhage	13 (2.5)	28 (3.8)
Brain contusion	17 (3.3)	22 (3.0)
Diffuse axonal injury	7 (1.3)	5 (0.7)
Causes of injury, n (%)			6.353	0.096
Non-accidental injury	207 (39.6)	253 (34.7)
Fall over injury	134 (25.6)	226 (31.0)
Traffic injury	73 (14.0)	114 (15.6)
High falling injury	109 (20.8)	136 (18.7)
iTBI – isolated traumatic brain injury; RBCs – red blood cells; GCS – Glasgow coma scale; AIS – abbreviated injury scale; ISS – injury severity score; LOS – the length of stay; ICU – Intensive Care Unit.