25 June 2020: Clinical Research
Serum Amyloid A: A Potential Biomarker Assessing Disease Activity in Systemic Lupus Erythematosus
Cai-Mei Wang EFG , Jin-Huan Deng EFG , Guo-Fei Mao B , Yong-Ling He B , Xiang Shi AC*DOI: 10.12659/MSM.923290
Med Sci Monit 2020; 26:e923290
Table 1 Demographic characteristics and laboratory parameters of patients with systemic lupus erythematosus (SLE) and healthy individuals.
| Patients with SLE | Healthy Controls | P-value | |
|---|---|---|---|
| n=135 | n=149 | ||
| Gender (Male/Female) | 14/121 | 22/127 | 0.266 |
| Age (years) | 38.0 (29.0–47.0) | 34.0 (26.0–44.0) | 0.085 |
| WBC (10/L) | 5.90 (3.98–9.24) | 6.68 (5.56–7.74) | 0.059 |
| RBC (10/L) | 4.10±0.67 | 4.54±0.37 | |
| Platelet count (10/L) | 224.56±91.09 | 250.35±37.89 | 0.003 |
| Hemoglobin (g/L) | 116.0 (105.0–125.0) | 133.0 (128.0–140.0) | |
| RDW (%) | 13.80 (12.90–15.90) | 12.20 (11.85–12.60) | |
| Hs-CRP (mg/L) | 2.35 (0.44–7.71) | 0.67 (0.58–0.99) | |
| ESR (mm/h) | 18.0 (11.0–35.0) | – | – |
| SAA (mg/L) | 4.90 (1.90–12.00) | – | – |
| SLEDAI-2k scores | 7.0 (5.0–15.0) | – | – |
| WBC – white blood cell count; RBC – red blood cell; RDW – red blood cell distribution width; Hs-CRP – hypersensitive C-reactive protein; ESR – erythrocyte sedimentation rate; SAA – serum amyloid A; SLEDAI-2K – SLE Disease Activity Index 2000. | |||