20 June 2020: Database Analysis
Increased Expression of T-Box Transcription Factor Protein 21 (TBX21) in Skin Cutaneous Melanoma Predicts Better Prognosis: A Study Based on The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) Databases
Xingying Zhang ADE* , Xin Wen ABE* , Ning Feng DE , Aoxin Chen DE , Senbang Yao DF , Xin Ding ADFG* , Longzhen Zhang ADG*DOI: 10.12659/MSM.923087
Med Sci Monit 2020; 26:e923087
Table 3 Univariate and multivariate Cox analysis of clinical factors and overall survival in SKCM patients.
| Clinical factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age | 1.0193 (1.0084–1.0302) | 1.0133 (1.0022–1.0245) | ||
| Gender | 1.0291 (0.7378–1.4355) | 0.8657 | 1.0430 (0.7438–1.4624) | 0.8073 |
| Stage | 1.3961 (1.1673–1.6699) | 1.0110 (0.7896–1.2945) | 0.9311 | |
| T stage | 1.3380 (1.1730–1.5261) | 1.3017 (1.1350–1.4929) | ||
| M stage | 1.7568 (0.7174–4.3020) | 0.2175 | 1.4131 (0.5433–3.6751) | 0.4783 |
| N stage | 1.4202 (1.2137–1.6620) | 1.4847 (1.1913–1.8504) | ||
| TBX21 | 0.6911 (0.5745–0.8315) | 0.7265 (0.6058–0.8713) | ||
| HR – hazard ratio; CI – confidence interval; SKCM – skin cutaneous melanoma | ||||