18 August 2020: Clinical Research
Risk Factors for Acquisition of Carbapenem-Resistant and Mortality Among Abdominal Solid Organ Transplant Recipients with Infections
Di Wu 1BCDE , Chunmei Chen 2CEF , Taohua Liu 3DE , Qiquan Wan 1ACDEFG*DOI: 10.12659/MSM.922996
Med Sci Monit 2020; 26:e922996
Table 2 Univariate and multivariate analysis of risk factors related to crude mortality in K. pneumoniae infection recipients.
| Characteristics | Mortality | Survival | P | OR (95% CI) |
|---|---|---|---|---|
| Total, n (%) | 20 (29.4) | 48 (70.6) | ||
| Age ≥40 years | 13 (65) | 32 (66.7) | 0.895 | |
| Male sex | 10 (50) | 33 (68.8) | 0.144 | |
| Temperature ≥39°C | 2 (10) | 2 (4.2) | 0.714 | |
| Inappropriate empirical antibiotics | 16 (80) | 21 (43.8) | 0.006* | |
| Nosocomial infection | 17 (85) | 24 (50) | 0.007* | |
| Liver transplantation | 6 (30) | 12 (25) | 0.670 | |
| bacteremia | 13 (65) | 11 (22.9) | 0.001* | |
| Early-onset infection | 15 (75) | 31 (64.6) | 0.581 | |
| Re-operation | 4 (20) | 4 (8.3) | 0.343 | |
| Multiple infected organisms or sites | 17 (85) | 11 (22.9) | * | |
| Mechanical ventilation | 7 (35) | 6 (12.5) | 0.070 | |
| The use of antithymocyte globulin | 8 (40) | 27 (56.3) | 0.222 | |
| The use of tacrolimus | 15 (75) | 42 (87.5) | 0.361 | |
| Septic shock | 6 (30) | 1 (2.1) | 0.003* | |
| Platelet count | 6 (30) | 5 (10.4) | 0.102 | |
| Lymphocyte count | 10 (50) | 15 (31.3) | 0.144 | |
| Albumin | 5 (25) | 4 (8.3) | 0.146 | |
| WBC count >15,000/mm | 7 (35) | 8 (16.7) | 0.180 | |
| Creatinine >1.5 mg/dL | 12 (60) | 26 (54.2) | 0.659 | |
| Carbapenem-resistant | 13 (65) | 25 (52.1) | 0.328 | |
| Multiple infected organisms or sites | 0.001* | 22.034 (4.348–111.653) | ||
| Septic shock | 0.016* | 27.090 (1.841–398.512) | ||
| -value from Pearson’s χ test or Fisher’s exact test in univariate analysis and from multiple logistic regression in multivariate analysis. * The -values are statistically significant. OR – odds ratio; CI – confidence interval; WBC – white blood cells. | ||||