22 June 2020>: Clinical Research
Association of Serum Thyroid Hormones with the Risk and Severity of Chronic Kidney Disease Among 3563 Chinese Adults
Jialin Li 1CE , Xi’ai Wu 2BD , Minjing Luo 1BF , Meihua Yan 3BD , Qian Wang 1D , Ping Li 3AG* , Wenquan Niu 3CE*DOI: 10.12659/MSM.922910
Med Sci Monit 2020; 26:e922910
Table 2 Risk prediction of thyroid hormones for chronic kidney disease (CKD) at different stages.
Significant risk factors | CKD Stage 1–2 | CKD Stage 3 | CKD Stage 4 | CKD Stage 5 |
---|---|---|---|---|
FT3 (+0.2 pg/mL) | 0.65, 0.60 to 0.73, | 0.60, 0.53 to 0.65, | 0.61, 0.57 to 0.67, | 0.99, 0.98 to 1.00, 0.088 |
FT4 (+0.3 ng/dL) | 0.65, 0.60 to 0.73, | 0.86, 0.69 to 1.07, 0.169 | 0.83, 0.71 to 0.98, 0.026 | 0.80, 0.71 to 0.91, 0.001 |
TSH (+0.5 μIU/mL) | 0.99, 0.93 to 1.06, 0.838 | 1.03, 0.98 to 1.08, 0.285 | 1.08, 1.03 to 1.14, 0.002 | 1.09, 1.03 to 1.15, 0.001 |
FT3 (+0.2 pg/mL) | 0.65, 0.58 to 0.72, | 0.62, 0.56 to 0.69, | 0.63, 0.58 to 0.69, | 0.98, 0.97 to 0.99, 0.005 |
FT4 (+0.3 ng/dL) | 0.76, 0.59 to 0.98, 0.034 | 0.84, 0.66 to 1.07, 0.151 | 0.83, 0.70 to 0.97, 0.022 | 0.79, 0.69 to 0.89, |
TSH (+0.5 μIU/mL) | 0.99, 0.92 to 1.06, 0.694 | 1.02, 0.97 to 1.08, 0.339 | 1.08, 1.02 to 1.14, 0.005 | 1.08, 1.02 to 1.14, 0.003 |
FT3 – free triiodothyronine; FT4 – free thyroxine; TSH – thyroid-stimulating hormone. Data are expressed as odds ratio, 95% confidence interval, P value. |