25 November 2020>: Database Analysis
Bioinformatics for The Prognostic Value and Function of Cubilin (CUBN) in Colorectal Cancer
Yibin Wu BCDEF , Ye Xu ACG*DOI: 10.12659/MSM.922447
Med Sci Monit 2020; 26:e922447
Table 1 Enrichment analysis of CUBN and its significant neighborhood genes altered in CRC as determined using DAVID.
Gene set | Description | Ontology | Count | P value |
---|---|---|---|---|
GO: 0042359 | Vitamin D metabolic process | BP | 3 | 9.6E-7 |
GO: 0051180 | Vitamin transport | BP | 2 | 8.9E-4 |
GO: 0042157 | Lipoprotein metabolic process | BP | 2 | 6.8E-3 |
GO: 0008203 | Cholesterol metabolic process | BP | 2 | 1.2E-2 |
GO: 0006898 | Receptor-mediated endocytosis | BP | 2 | 3.3E-2 |
GO: 0030139 | Endocytic vesicle | CC | 3 | 3.4E-5 |
GO: 0072562 | Blood microparticle | CC | 3 | 1.8E-4 |
GO: 0070062 | Extracellular exosome | CC | 5 | 5.8E-4 |
GO: 0034366 | Spherical high-density lipoprotein particle | CC | 2 | 2.2E-3 |
GO: 0042627 | Chylomicron | CC | 2 | 3.3E-3 |
GO: 0070653 | High-density lipoprotein particle receptor binding | MF | 2 | 1.3E-3 |
GO: 0008035 | High-density lipoprotein particle binding | MF | 2 | 2.0E-3 |
GO: 0060228 | Phosphatidylcholine-sterol O-acyltransferase activator activity | MF | 2 | .6E-3 |
GO: 0017127 | Cholesterol transporter activity | MF | 2 | 5.3E-3 |
GO: 0031210 | Phosphatidylcholine binding | MF | 2 | 5.6E-3 |
hsa04977 | Vitamin digestion and absorption | KP | 2 | 0.006 |
GO – Gene Ontology; BP – biological process; CC – cellular component. MF; molecular function. KP – KEGG pathway. |