21 August 2020>: Animal Study
Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model
Minghong Deng 1ACE , Chunwang Lin 1AE* , Xianglin Zeng 1C , Jianping Zhang 1BD , Fang Wen 1C , Ziguang Liu 2B , Haiyan Wu 3B , Xiaofeng Wu 4BDOI: 10.12659/MSM.922429
Med Sci Monit 2020; 26:e922429
Table 1 Comparison of IRS values for p53, p21, Bcl2, and caspase-3 between the KD and control groups.
Group | n | p53 IRS | p21 IRS | Bcl2 IRS | Caspase-3 IRS |
---|---|---|---|---|---|
KD | 12 | 5.33±0.90 | 5.07±0.70 | 4.43±0.51 | 5.60±0.50 |
Control | 12 | 4.05±1.05 | 3.21±0.97 | 6.37±0.76 | 3.83±0.38 |
4.61 | 5.30 | 5.79 | 5.24 | ||
0.001 | 0.001 | 0.001 | 0.001 |