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04 June 2019 : Animal Research

Loganin Attenuates Osteoarthritis in Rats by Inhibiting IL-1β-Induced Catabolism and Apoptosis in Chondrocytes Via Regulation of Phosphatidylinositol 3-Kinases (PI3K)/Akt

Yi Yang1BCE, Yuntao Gu1CDF, Hai Zhao1BF, Shunli Zhang1AG*

DOI: 10.12659/MSM.915064

Med Sci Monit 2019; 25:4159-4168

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02 Jan 2020 : Laboratory Research

S100A16 Regulates HeLa Cell through the Phosphatidylinositol 3 Kinase (PI3K)/AKT Signaling Pathway

Haibin Zhang, Yongxiu Yang [...]

DOI: 10.12659/MSM.919757

Med Sci Monit 2020; 26:e919757

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03 Mar 2020 : Animal Research

Promotion of G1/S Transition and Inhibition of Inflammatory Cytokine Production by Hydroxypyridinone-Coumarin in Osteoarthritis Rats

Kai Yang, Gang Chen [...]

DOI: 10.12659/MSM.920784

Med Sci Monit 2020; 26:e920784

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12 Jan 2020 : Animal Research

Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis

ShaoWen Cheng, Lei Peng [...]

DOI: 10.12659/MSM.920211

Med Sci Monit 2020; 26:e920211

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07 Apr 2020 : Database Analysis

Sex Differences in Osteoarthritis Pathogenesis: A Comprehensive Study Based on Bioinformatics

Yunfeng Yang, Xiaomeng You [...]

DOI: 10.12659/MSM.923331

Med Sci Monit 2020; 26:e923331

84 1 29

09 Jul 2020 : Laboratory Research

Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis

Yunping Chen, Hongna Guo [...]

DOI: 10.12659/MSM.923868

Med Sci Monit 2020; 26:e923868

95 1 27

09 Jan 2020 : Animal Research

Proteomics and Bioinformatics Analysis of Cartilage in Post-Traumatic Osteoarthritis in a Mini-Pig Model of Anterior Cruciate Ligament Repair

Pengcui Li, Xianda Che [...]

DOI: 10.12659/MSM.920104

Med Sci Monit 2020; 26:e920104

85 0 27

20 Mar 2019 : Laboratory Research

A Long Noncoding RNA (lncRNA)-Associated Competing Endogenous RNA (ceRNA) Network Identifies Eight lncRNA Biomarkers in Patients with Osteoarthritis of the Knee

Yuxi Chen, Yu Lin [...]

DOI: 10.12659/MSM.915555

Med Sci Monit 2019; 25:2058-2065

101 3 42

13 Apr 2019 : Animal Research

A Novel Rat Model of Patellofemoral Osteoarthritis Due to Patella Baja, or Low-Lying Patella

Mingjian Bei, Faming Tian [...]

DOI: 10.12659/MSM.915018

Med Sci Monit 2019; 25:2702-2717

146 2 35

29 Apr 2019 : Animal Research

Estrogen Modulates Cartilage and Subchondral Bone Remodeling in an Ovariectomized Rat Model of Postmenopausal Osteoarthritis

Xiao Xu, Xingfu Li [...]

DOI: 10.12659/MSM.916254

Med Sci Monit 2019; 25:3146-3153

260 16 42

26 Oct 2019 : Clinical Research

Long Non-Coding RNA (LncRNA) CAIF is Downregulated in Osteoarthritis and Inhibits LPS-Induced Interleukin 6 (IL-6) Upregulation by Downregulation of MiR-1246

Ke Qi, Rongqiang Lin [...]

DOI: 10.12659/MSM.917135

Med Sci Monit 2019; 25:8019-8024

58 2 51

05 Sep 2019 : Animal Research

Catalpol Attenuates IL-1β Induced Matrix Catabolism, Apoptosis and Inflammation in Rat Chondrocytes and Inhibits Cartilage Degeneration

Yun-fu Zeng, Rong Wang [...]

DOI: 10.12659/MSM.916209

Med Sci Monit 2019; 25:6649-6659

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05 Aug 2019 : Laboratory Research

Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition

Mingzheng Wu, Rui Hu [...]

DOI: 10.12659/MSM.917851

Med Sci Monit 2019; 25:5833-5840

106 0 23

16 Jun 2019 : Laboratory Research

Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway

Jiajia Chen, Zemian Chen [...]

DOI: 10.12659/MSM.916202

Med Sci Monit 2019; 25:4474-4484

103 5 44

10 Jun 2019 : Laboratory Research

microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract

Yan Liu, Huanhuan Li [...]

DOI: 10.12659/MSM.916881

Med Sci Monit 2019; 25:4314-4321

41 1 55

14 Aug 2019 : Clinical Research

Network Pharmacology Identifies the Mechanisms of Action of Shaoyao Gancao Decoction in the Treatment of Osteoarthritis

Naiqiang Zhu, Jingyi Hou [...]

DOI: 10.12659/MSM.915821

Med Sci Monit 2019; 25:6051-6073

605 19 31

21 Aug 2019 : Laboratory Research

Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes

Peng-Fei Hu, Fang-Fang Sun [...]

DOI: 10.12659/MSM.916039

Med Sci Monit 2019; 25:6271-6280

62 1 11

28 Aug 2019 : Animal Research

High-Mobility Group Box 1 (HMGB1) Induces Migration of Endothelial Progenitor Cell via Receptor for Advanced Glycation End-Products (RAGE)-Dependent PI3K/Akt/eNOS Signaling Pathway

Yulong Zhang, Bo You [...]

DOI: 10.12659/MSM.915829

Med Sci Monit 2019; 25:6462-6473

149 1 25

09 Sep 2019 : Laboratory Research

A Novel Chinese Medicine, Xinfeng Capsule, Modulates Proinflammatory Cytokines via Regulating the Toll-Like Receptor 4 (TLR4)/Mitogen-Activated Protein Kinase (MAPK)/Nuclear Kappa B (NF-κB) Signaling Pathway in an Adjuvant Arthritis Rat Model

Yun-Xiang Cao, Dan Huang [...]

DOI: 10.12659/MSM.916317

Med Sci Monit 2019; 25:6767-6774

78 1 26

06 Oct 2019 : Animal Research

Xanthan Gum Ameliorates Osteoarthritis and Mitigates Cartilage Degradation via Regulation of the Wnt3a/β-Catenin Signaling Pathway

Jingyuan Li, Guanying Han [...]

DOI: 10.12659/MSM.916092

Med Sci Monit 2019; 25:7488-7498

108 0 48

28 Oct 2019 : Laboratory Research

Long Noncoding RNA Nuclear Enriched Abundant Transcript 1 (NEAT1) Regulates Proliferation, Apoptosis, and Inflammation of Chondrocytes via the miR-181a/Glycerol-3-Phosphate Dehydrogenase 1-Like (GPD1L) Axis

Zengliang Wang, Jianxue Hao [...]

DOI: 10.12659/MSM.918416

Med Sci Monit 2019; 25:8084-8094

83 1 92

12 Feb 2018 : Clinical Research

Detection of miR-22, miR-140 and Bone Morphogenetic Proteins (BMP)-2 Expression Levels in Synovial Fluid of Osteoarthritis Patients Before and After Arthroscopic Debridement

Renjun Yang, Dianying Zhang [...]

DOI: 10.12659/MSM.908110

Med Sci Monit 2018; 24: CLR863-868

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23 May 2018 : Animal Research

A Macaca Fascicularis Knee Osteoarthritis Model Developed by Modified Hulth Combined with Joint Scratches

Xin Zhou, Lei Zhang [...]

DOI: 10.12659/MSM.906626

Med Sci Monit 2018; 24: ANS3393-3404

112 0 40

19 Sep 2018 : Animal Research

Protective Effects of Oleuropein Against Cerebral Ischemia/Reperfusion by Inhibiting Neuronal Apoptosis

Weijing Zhang, Xiaogang Liu [...]

DOI: 10.12659/MSM.912336

Med Sci Monit 2018; 24: ANS6587-6598

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01 Jul 2018 : Animal Research

Selection and Investigation of a Primate Model of Spontaneous Degenerative Knee Osteoarthritis, the Cynomolgus Monkey (Macaca Fascicularis)

Gang Liu, Lei Zhang [...]

DOI: 10.12659/MSM.908913

Med Sci Monit 2018; 24: ANS4516-4527

61 0 29

09 Sep 2018 : Laboratory Research

Marsdenia Tenacissima Extract Inhibits Proliferation and Promotes Apoptosis in Human Ovarian Cancer Cells

Yuhong Zhang, Yangjia Zhang

DOI: 10.12659/MSM.909726

Med Sci Monit 2018; 24: LBR6289-6297

60 2 52

09 Jul 2018 : Clinical Research

Origin and Efficacy of Hyaluronan Injections in Knee Osteoarthritis: Randomized, Double-Blind Trial

Yuanli Guo, Peiyan Yang [...]

DOI: 10.12659/MSM.908797

Med Sci Monit 2018; 24: CLR4728-4737

99 2 34

18 Mar 2018 : Animal Research

Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage

Wenqian Zhang, Ying Cui [...]

DOI: 10.12659/MSM.905700

Med Sci Monit 2018; 24: ANS1588-1596

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23 Sep 2018 : Animal Research

Icariin Reduces Cartilage Degeneration in a Mouse Model of Osteoarthritis and is Associated with the Changes in Expression of Indian Hedgehog and Parathyroid Hormone-Related Protein

Yuan Luo, Yiwen Zhang [...]

DOI: 10.12659/MSM.910983

Med Sci Monit 2018; 24: ANS6695-6706

84 2 46

17 Dec 2018 : Animal Research

Effects of Hesperidin on H₂O₂-Treated Chondrocytes and Cartilage in a Rat Osteoarthritis Model

Gongming Gao, Huimin Ding [...]

DOI: 10.12659/MSM.913726

Med Sci Monit 2018; 24: ANS9177-9186

122 2 44

20 Aug 2018 : Clinical Research

Clinical Outcome of Sodium Hyaluronate Injection into the Superior and Inferior Joint Space for Osteoarthritis of the Temporomandibular Joint Evaluated by Cone-Beam Computed Tomography: A Retrospective Study of 51 Patients and 56 Joints

Haibin Sun, Yi Su [...]

DOI: 10.12659/MSM.908821

Med Sci Monit 2018; 24: CLR5793-5801

92 1 26

10 Mar 2017 : Laboratory Research

miR-181a Modulates Chondrocyte Apoptosis by Targeting Glycerol-3-Phosphate Dehydrogenase 1-Like Protein (GPD1L) in Osteoarthritis

Xicheng Zhai, Ru Meng [...]

DOI: 10.12659/MSM.899228

Med Sci Monit 2017; 23:1224-1231

62 0 30

02 Aug 2017 : Animal Research

Effect of Naringin on Monosodium Iodoacetate-Induced Osteoarthritis Pain in Rats

Qiang Xu, Zuo-fu Zhang [...]

DOI: 10.12659/MSM.902396

Med Sci Monit 2017; 23:3746-3751

105 2 21

14 Aug 2017 : Laboratory Research

Kaempferol Alleviates the Interleukin-1β-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-κB

Zhengling Zhuang, Guangqun Ye [...]

DOI: 10.12659/MSM.902491

Med Sci Monit 2017; 23:3925-3931

78 3 44

07 Nov 2017 : Animal Research

Cross-Coupling Effects of Silencing of Cyclooxygenase-2 (COX-2)/Aggrecanase-1 and Over-Expressed Insulin-Like Growth Factor 1 (IGF-1) in an Osteoarthritis Animal Model

Zhao Zhang, Xiaofei Li [...]

DOI: 10.12659/MSM.907150

Med Sci Monit 2017; 23:5302-5310

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01 Dec 2017 : Clinical Research

Characteristics of Plantar Loads During Walking in Patients with Knee Osteoarthritis

Zhiwang Zhang, Lin Wang [...]

DOI: 10.12659/MSM.905136

Med Sci Monit 2017; 23:5714-5719

82 1 43

20 Jun 2016 : Clinical Research

Expression and Significance of High-Mobility Group Protein B1 (HMGB1) and the Receptor for Advanced Glycation End-Product (RAGE) in Knee Osteoarthritis

Xue-Hui Sun, Ying Liu [...]

DOI: 10.12659/MSM.895689

Med Sci Monit 2016; 22:2105-2112

76 0 31

25 Jun 2016 : Clinical Research

Synovial Fluid Macrophage Migration Inhibitory Factor Levels Correlate with Severity of Self-Reported Pain in Knee Osteoarthritis Patients

Pei-liang Zhang, Jun Liu [...]

DOI: 10.12659/MSM.895704

Med Sci Monit 2016; 22:2182-2186

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25 Jul 2016 : Clinical Research

A Water Rehabilitation Program in Patients with Hip Osteoarthritis Before and After Total Hip Replacement

Marek Łyp, Ryszard Kaczor [...]

DOI: 10.12659/MSM.896203

Med Sci Monit 2016; 22:2635-2642

329 30 24

06 Aug 2016 : Clinical Research

Correlation of Adrenomedullin Concentrations with Knee Osteoarthritis Grade

Linghua Liu, Ruokun Huang [...]

DOI: 10.12659/MSM.896987

Med Sci Monit 2016; 22:2775-2778

47 1 31

29 Oct 2016 : Clinical Research

Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis

Jun Yi, Qunhua Jin [...]

DOI: 10.12659/MSM.897849

Med Sci Monit 2016; 22:4062-4065

70 1 32

17 Apr 2016 : Animal Research

Advantages of Pure Platelet-Rich Plasma Compared with Leukocyte- and Platelet-Rich Plasma in Treating Rabbit Knee Osteoarthritis

Wen-Jing Yin, Hai-Tao Xu [...]

DOI: 10.12659/MSM.898218

Med Sci Monit 2016; 22:1280-1290

144 0 34

30 Jan 2015 : Clinical Research

Correlation of Bone Morphogenetic Protein-2 Levels in Serum and Synovial Fluid with Disease Severity of Knee Osteoarthritis

Yan Liu, Ruizhi Hou [...]

DOI: 10.12659/MSM.892160

Med Sci Monit 2015; 21:363-370

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21 Mar 2015 : Clinical Research

Serum and Synovial Fluid Levels of CCL18 are Correlated with Radiographic Grading of Knee Osteoarthritis

Yun Zhou, Juwu Chen [...]

DOI: 10.12659/MSM.892409

Med Sci Monit 2015; 21:840-844

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15 Apr 2015 : Clinical Research

Serum and Synovial Fluid Nesfatin-1 Concentration is Associated with Radiographic Severity of Knee Osteoarthritis

Yusong Zhang, Xiaolong Shui [...]

DOI: 10.12659/MSM.892875

Med Sci Monit 2015; 21:1078-1082

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15 Jun 2015 : Clinical Research

Correlation of IL-17 Level in Synovia and Severity of Knee Osteoarthritis

Yingsong Liu, Hao Peng [...]

DOI: 10.12659/MSM.893771

Med Sci Monit 2015; 21:1732-1736

74 2 28

26 Jan 2014 : Clinical Research

Relationship of acetabular dysplasia in females with osteoarthritis of the hip to the distance between both anterior superior iliac spines

Kunihiko Okano, Seiya Jingushi [...]

DOI: 10.12659/MSM.889704

Med Sci Monit 2014; 20:116-122

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20 Nov 2014 : Original article

Mid-Term Results of Metal-on-Metal Hip Resurfacing for Treatment of Osteoarthritis Secondary to Developmental Dysplasia of the Hip: A Minimum of 8-Years of Follow-Up

Yuxing Qu, Tao Jiang [...]

DOI: 10.12659/MSM.890892

Med Sci Monit 2014; 20:2363-2368

68 0 29

01 Dec 2014 : Case report

Knee Joint Pain Potentially Due to Bone Alterations in a Knee Osteoarthritis Patient

Masatoshi Komatsu, Yukio Nakamura [...]

DOI: 10.12659/AJCR.891233

Am J Case Rep 2014; 15:534-537

106 2 31

26 Nov 2013 : Original article

L-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in plasma and synovial fluid of patients with knee osteoarthritis

Valerio Pascale, Walter Pascale [...]

DOI: 10.12659/MSM.889275

Med Sci Monit 2013; 19:1057-1062

57 0 42

01 Jun 2012

Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte

Yunsheng Ou, Chao Tan [...]

DOI: 10.12659/MSM.882901

Med Sci Monit 2012; 18(6): BR247-252

55 0 32

28 Apr 2010

Oxidative equilibrium in the prophylaxis of degenerative joint changes: an analysis of pre- and postoperative activity of antioxidant enzymes in patients with hip and knee osteoarthritis

Dorota Olszewska-Slonina, Dariusz Matewski [...]

Med Sci Monit 2010; 16(5): CR238-245

56 1 38

23 Jun 2009

Unilateral developments of osteoarthritis and Charcot's joint in a patient with neurofibromatosis

Yoshihiro Matsukawa, Hiroyuki Hara [...]

Med Sci Monit 2009; 15(7): CS113-116

53 1 31

01 Apr 2008

Differences in WHOQOL-100 domain scores in Parkinson’s disease and osteoarthritis

Vaineta Valeikiene, Jelena Ceremnych [...]

Med Sci Monit 2008; 14(4): CR221-227

35 2 22

Editorial

01 January 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

SARS-CoV-2/COVID-19

25 January 2022 : Editorial  

Editorial: The 2022 World Health Organization (WHO) Priority Recommendations and Response to the Omicron Va...

Med Sci Monit In Press; DOI: 10.12659/MSM.936199  

25 January 2022 : Clinical Research  

Experience of the Polish Medical Air Rescue Service During the First Year of the COVID-19 Pandemic and Meas...

Med Sci Monit In Press; DOI: 10.12659/MSM.935474  

11 January 2022 : Clinical Research  

A Remote Questionnaire-Based Study to Compare Alcohol Use in 1030 Final-Year High School Students in Split-...

Med Sci Monit In Press; DOI: 10.12659/MSM.935567  

31 December 2021 : Clinical Research  

A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus...

Med Sci Monit 2021; 27:e935075

In Press

25 Jan 2022 : Editorial  

Editorial: The 2022 World Health Organization (WHO) Priority Recommendations and Response to the Omicron Va...

Med Sci Monit In Press; DOI: 10.12659/MSM.936199  

25 Jan 2022 : Clinical Research  

Experience of the Polish Medical Air Rescue Service During the First Year of the COVID-19 Pandemic and Meas...

Med Sci Monit In Press; DOI: 10.12659/MSM.935474  

24 Jan 2022 : Clinical Research  

Causes of Lower Respiratory Tract Infections and the Use of Diagnostic Biomarkers in Blood Samples from Chi...

Med Sci Monit In Press; DOI: 10.12659/MSM.934889  

19 Jan 2022 : Clinical Research  

A Retrospective Study to Compare the Effects of Methylprednisolone and Dexamethasone in 35 Patients with An...

Med Sci Monit In Press; DOI: 10.12659/MSM.934703  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

05 Mar 2020 : Clinical Research  

The Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease ...

DOI :10.12659/MSM.923549

Med Sci Monit 2020; 26:e923549

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750