11 February 2018 : Laboratory Research
Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway
DOI: 10.12659/MSM.907814
Med Sci Monit 2018; 24: LBR846-854
Related articles
28 Jan 2019 : Laboratory Research
Sulforaphane Attenuates H₂O₂-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation
Yuzhen Liu, Pan Liu
DOI: 10.12659/MSM.913849
Med Sci Monit 2019; 25:811-818
21 Oct 2019 : Laboratory Research
Antiproliferative Activity of Carnosic Acid is Mediated via Inhibition of Cell Migration and Invasion, and Suppression of Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway
Liqun Zhao, Juanni Zhang
DOI: 10.12659/MSM.917735
Med Sci Monit 2019; 25:7864-7871
27 Dec 2019 : Laboratory Research
miR-206 Inhibits Cell Proliferation and Extracellular Matrix Accumulation by Targeting Hypoxia-Inducible Factor 1-alpha (HIF-1α) in Mesangial Cells Treated with High Glucose
Yanchao Cao, Xufen Cao
DOI: 10.12659/MSM.918912
Med Sci Monit 2019; 25:10036-10044
18 Jul 2018 : Animal Research
Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway
Jiaxuan He, Jianfang Zhu
DOI: 10.12659/MSM.909056
Med Sci Monit 2018; 24: ANS4982-4991
14 Feb 2017 : Animal Research
Evaluating the Effectiveness of GTM-1, Rapamycin, and Carbamazepine on Autophagy and Alzheimer Disease
Lijuan Zhang, Lina Wang
DOI: 10.12659/MSM.898679
Med Sci Monit 2017; 23:801-808
27 Apr 2017 : Laboratory Research
Mammalian Target of Rapamycin (mTOR) Regulates Transforming Growth Factor-β1 (TGF-β1)-Induced Epithelial-Mesenchymal Transition via Decreased Pyruvate Kinase M2 (PKM2) Expression in Cervical Cancer Cells
Ke-yan Cheng, Min Hao
DOI: 10.12659/MSM.901542
Med Sci Monit 2017; 23:2017-2028
28 Apr 2017 : Laboratory Research
Lycorine Induces Apoptosis of A549 Cells via AMPK-Mammalian Target of Rapamycin (mTOR)-S6K Signaling Pathway
Hui Zeng, Rong Fu
DOI: 10.12659/MSM.900742
Med Sci Monit 2017; 23:2035-2041
30 Jun 2017 : Clinical Research
Prognostic Significance of Periostin and Mammalian Target of Rapamycin (mTOR) in Locally Advanced Esophageal Squamous Cell Carcinoma
Qi Jiang, Jingjing Chen
DOI: 10.12659/MSM.904992
Med Sci Monit 2017; 23:3200-3208
21 Jul 2017 : Animal Research
Roles of Mitogen-Activating Protein Kinase Kinase Kinase Kinase-3 (MAP4K3) in Preterm Skeletal Muscle Satellite Cell Myogenesis and Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Regulation
Chu-yi Guo, Mu-xue Yu
DOI: 10.12659/MSM.902553
Med Sci Monit 2017; 23:3562-3570
30 Aug 2017 : Clinical Research
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway
Weipeng Zhao, Xichuan Li
DOI: 10.12659/MSM.906389
Med Sci Monit 2017; 23:4182-4191
05 Jun 2017 : Case report
Rapamycin Treatment for Benign Multicystic Peritoneal Mesothelioma: A Rare Disease with a Difficult Management
Giovanni Stallone, Barbara Infante
DOI: 10.12659/AJCR.903548
Am J Case Rep 2017; 18:632-636
25 Oct 2016 : Animal Research
Long-Term Alcohol-Induced Activation of Mammalian Target of Rapamycin is a Key Risk Factor of Epilepsy
Xiaoling Fu, Zhe Guo
DOI: 10.12659/MSM.897018
Med Sci Monit 2016; 22:3975-3980
29 Nov 2016 : Laboratory Research
Isoflurane Promotes Non-Small Cell Lung Cancer Malignancy by Activating the Akt-Mammalian Target of Rapamycin (mTOR) Signaling Pathway
Wenhua Zhang, Xueqian Shao
DOI: 10.12659/MSM.898434
Med Sci Monit 2016; 22:4644-4650
13 Feb 2015 : Animal Research
Effects of Rapamycin on Reduction of Peridural Fibrosis: An Experimental Study
Like Luo, Chifei Zhang
DOI: 10.12659/MSM.893165
Med Sci Monit 2015; 21:482-488
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952