Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer

Related articles

19 Apr 2020 : Clinical Research

Influence of Hypertension on the Survival of Non-Small Cell Lung Cancer Patients with Type 2 Diabetes Mellitus

Xianghua Zeng, Dong Zeng, [...] Jianan Cheng, Cheng Xu, Chengdu Sun, Haixia Long, Bo Zhu - Show fewer authors

DOI: 10.12659/MSM.921676

04 Jan 2020 : Laboratory Research

Induction of Apoptosis in Lung Cancer Cells by Viburnum grandiflorum via Mitochondrial Pathway

Bing Han, Jianqiang Wu, [...] Lei Huang - Show fewer authors

DOI: 10.12659/MSM.920265

13 Jan 2020 : Case report

Venous Sinus Stenting for Transverse Sinus Stenosis Associated with Leptomeningeal Carcinomatosis in a Patient with Epidermal Growth Factor Receptor-Mutated Lung Cancer: A Case Report

Yasuhiro Kawabata, Norio Nakajima, [...] Hidenori Miyake, Yasumasa Yamamoto, Shintaro Toda, Yasuji Terada, Mamoru Takahashi, Masafumi Kurimoto - Show fewer authors

DOI: 10.12659/AJCR.918488

28 Jan 2019 : Laboratory Research

Sulforaphane Attenuates H₂O₂-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation

Yuzhen Liu, Pan Liu, [...] Qiang Wang, Fengmei Sun, Fang Liu - Show fewer authors

DOI: 10.12659/MSM.913849

29 May 2019 : Laboratory Research

Gambogic Acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced Endoplasmic Reticulum (ER) Stress-Mediated Apoptosis

Minghua Zhu, Yinfang Jiang, [...] Hao Wu, Wei Shi, Guirong Lu, Degang Cong, Keyuan Liu, Shaohui Song, Jianming Ren - Show fewer authors

DOI: 10.12659/MSM.916835

29 Aug 2018 : Clinical Research

lncRA ANCR Inhibits Non-Small Cell Lung Cancer Cell Migration and Invasion by Inactivating TGF-β Pathway

Shaobin Wang, Fen Lan, [...] Yang Xia - Show fewer authors

DOI: 10.12659/MSM.911492

07 Oct 2018 : Laboratory Research

Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling

Minghua Zhu, Minjie Wang, [...] Yinfang Jiang, Hao Wu, Guirong Lu, Wei Shi, Degang Cong, Shaohui Song, Keyuan Liu, Hao Wang - Show fewer authors

DOI: 10.12659/MSM.912563

21 Oct 2018 : Laboratory Research

Methylenetetrahydrofolate Dehydrogenase 1 Silencing Expedites the Apoptosis of Non-Small Cell Lung Cancer Cells via Modulating DNA Methylation

Ke Ding, Jianyang Jiang, [...] Liang Chen, Xiaohua Xu - Show fewer authors

DOI: 10.12659/MSM.910265

11 Nov 2018 : Laboratory Research

Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling

Xiaohua Xu, Jianyang Jiang, [...] Lijuan Yao, Bing Ji - Show fewer authors

DOI: 10.12659/MSM.911384

15 Nov 2018 : Clinical Research

Comparison of Rearranged During Transfection (RET) Gene Rearrangements in Primary Versus Metastatic Non-Small Cell Lung Cancer (NSCLC)

Quxia Zhang, Chunwei Xu, [...] Wenxian Wang, Meijuan Wu, Youcai Zhu, Wu Zhuang, Kaiqi Du, Yunjian Huang, Yanping Chen, Biao Wu - Show fewer authors

DOI: 10.12659/MSM.911634

31 Dec 2018 : Laboratory Research

Serum Fork-Head Box D3 (FOXD3) Expression Is Down-Regulated in and Associated with Diagnosis of Patients with Non-Small Cell Lung Cancer

Bao-Ning Xu, Lei Zhang, [...] Dan-Dan Zhang, Cheng-Yang Song, Da-Li Tian, Wen-Jun Jiang - Show fewer authors

DOI: 10.12659/MSM.896748

11 Jan 2018 : Laboratory Research

Actin Filament-Associated Protein 1-Like 1 Mediates Proliferation and Survival in Non-Small Cell Lung Cancer Cells

Meng Wang, Xingpeng Han, [...] Wei Sun, Xin Li, Guohui Jing, Xun Zhang - Show fewer authors

DOI: 10.12659/MSM.905900

01 Mar 2018 : Laboratory Research

Glutamine Enhances the Hypoglycemic Effect of Insulin in L6 Cells via Phosphatidylinositol-3-Kinase (PI3K)/Protein Kinase B (AKT)/Glucose Transporter 4 (GLUT4) Signaling Pathway

Caijuan Wang, Yujiao Deng, [...] Yenan Yue, Wenting Chen, Yu Zhang, Guifang Shi, Zhongming Wu - Show fewer authors

DOI: 10.12659/MSM.909011

27 Mar 2018 : Case report

Resolution of Infliximab-Refractory Nivolumab-Induced Acute Severe Enterocolitis After Cyclosporine Treatment in a Patient with Non-Small Cell Lung Cancer

Tomokazu Iyoda, Noriaki Kurita, [...] Ayumi Takada, Hiroe Watanabe, Masahiro Ando - Show fewer authors

DOI: 10.12659/AJCR.908570

12 Jun 2016 : Laboratory Research

DNA Repair Genes ERCC1 and BRCA1 Expression in Non-Small Cell Lung Cancer Chemotherapy Drug Resistance

Shuai Wang, Feng Liu, [...] Jingyan Zhu, Peng Chen, Hongxing Liu, Qi Liu, Junqing Han - Show fewer authors

DOI: 10.12659/MSM.896606

10 Apr 2018 : Laboratory Research

Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway

Jiawen You, Jun Cheng, [...] Bing Yu, Changhua Duan, Jinghua Peng - Show fewer authors

DOI: 10.12659/MSM.909627

10 May 2016 : Laboratory Research

High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy

Weihua Zhang, Jian Sun, [...] Junming Luo - Show fewer authors

DOI: 10.12659/MSM.898632

03 May 2018 : Laboratory Research

Interleukin-22 (IL-22) Regulates Apoptosis of Paclitaxel-Resistant Non-Small Cell Lung Cancer Cells Through C-Jun N-Terminal Kinase Signaling Pathway

Chenchen Li, Xia Zhao, [...] Yang Yang, Siwen Liu, Yun Liu, Xiaoyou Li - Show fewer authors

DOI: 10.12659/MSM.907336

23 Jun 2016 : Animal Research

Astaxanthin Inhibits Proliferation and Induces Apoptosis and Cell Cycle Arrest of Mice H22 Hepatoma Cells

Yiye Shao, Yanbo Ni, [...] Jing Yang, Xutao Lin, Jun Li, Lixia Zhang - Show fewer authors

DOI: 10.12659/MSM.899419

30 May 2018 : Case report

Silent Neoplastic Cardiac Invasion in Small Cell Lung Cancer: A Case Report and Review of the Literature

Ngoc Pham, Mark D. Bonnen, [...] Yohannes T. Ghebre - Show fewer authors

DOI: 10.12659/AJCR.908374

21 Jul 2016 : Clinical Research

Five-Year Survival Among Stage IIIA Lung Cancer Patients Receiving Two Different Treatment Modalities

Thomas Bilfinger, Roger Keresztes, [...] Denise Albano, Barbara Nemesure - Show fewer authors

DOI: 10.12659/MSM.898675

18 Oct 2016 : Laboratory Research

Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis

Shuichuan Song, Leiwen Du, [...] Hao Jiang, Xinhai Zhu, Jinhui Li, Ji Xu - Show fewer authors

DOI: 10.12659/MSM.898232

23 Nov 2016 : Case report

Nivolumab-Induced Severe Akathisia in an Advanced Lung Cancer Patient

Jiro Abe, Taku Sato, [...] Ryota Tanaka, Toshimasa Okazaki, Satomi Takahashi - Show fewer authors

DOI: 10.12659/AJCR.900941

15 Jan 2017 : Clinical Research

Fibroblast Growth Factor Receptor 1 (FGFR1), Partly Related to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) and Microvessel Density, is an Independent Prognostic Factor for Non-Small Cell Lung Cancer

Dan Pu, Jiewei Liu, [...] Zhixi Li, Jiang Zhu, Mei Hou - Show fewer authors

DOI: 10.12659/MSM.899005

11 Apr 2016 : Clinical Research

Does Every Necrotizing Granulomatous Inflammation Identified by NSCLC Resection Material Require Treatment?

Fatih Yakar, Aysun Yakar, [...] Nur Büyükpınarbaşılı, Mustafa Erelel - Show fewer authors

DOI: 10.12659/MSM.897638

27 Jan 2017 : Laboratory Research

The Utility of Thyroid Transcription Factor 1 (TTF-1), Napsin A, Excision Repair Cross-Complementing 1 (ERCC1), Anaplastic Lymphoma Kinase (ALK) and the Epidermal Growth Factor Receptor (EGFR) Expression in Small Biopsy in Prognosis of Patients with Lung Adenocarcinoma – A Retrograde Single-Center Study from Croatia

Marina Piljić Burazer, Suzana Mladinov, [...] Vesna Ćapkun, Sendi Kuret, Merica Glavina Durdov - Show fewer authors

DOI: 10.12659/MSM.899378

26 Feb 2016 : Clinical Research

Increased Plasma miRNA-30a as a Biomarker for Non-Small Cell Lung Cancer

Ling Sun, Yifan Chen, [...] Qiaoli Su, Xiaoju Tang, Yasha Liang, Guowei Che, Fengming Luo - Show fewer authors

DOI: 10.12659/MSM.897330

09 Mar 2017 : Clinical Research

PD-1, PD-L1 Protein Expression in Non-Small Cell Lung Cancer and Their Relationship with Tumor-Infiltrating Lymphocytes

Yayi He, Leslie Rozeboom, [...] Christopher J. Rivard, Kim Ellison, Rafał Dziadziuszko, Hui Yu, Caicun Zhou, Fred R. Hirsch - Show fewer authors

DOI: 10.12659/MSM.899909

03 Jan 2016 : Clinical Research

Modulation of Cytokines in Cancer Patients by Intravenous Ascorbate Therapy

Nina Mikirova, Neil Riordan, [...] Joseph Casciari - Show fewer authors

DOI: 10.12659/MSM.895368

25 Jul 2017 : Clinical Research

Correlation Between Circulating Tumor DNA Levels and Response to Tyrosine Kinase Inhibitors (TKI) Treatment in Non-Small Cell Lung Cancer

Zhangjing Wei, Wenyue Wang, [...] Zitan Shu, Xue Zhou, Yanfang Zhang - Show fewer authors

DOI: 10.12659/MSM.902265

26 Nov 2017 : Clinical Research

PI3K-Akt Signal Transduction Molecules Maybe Involved in Downregulation of Erythroblasts Apoptosis and Perifosine Increased Its Apoptosis in Chronic Mountain Sickness

Chengyu Zhao, Zhanquan Li, [...] Linhua Ji, Jie Ma, Ri-Li Ge, Sen Cui - Show fewer authors

DOI: 10.12659/MSM.905739

07 Aug 2010

Cytosolic phospholipase A2 group IVA influence on GM-CSF expression in human lung cells: A pilot study

Milena Sokolowska, Joanna Stefanska, [...] Karolina Wodz-Naskiewicz, Rafal Pawliczak - Show fewer authors

24 Dec 2017 : Laboratory Research

Long Non-Coding RNA Prostate Cancer-Associated Transcript 7 (PCAT7) Induces Poor Prognosis and Promotes Tumorigenesis by Inhibiting mir-134-5p in Non-Small-Cell Lung (NSCLC)

Qiongliang Liu, Yingying Wu, [...] Jie Xiao, Jianyong Zou - Show fewer authors

DOI: 10.12659/MSM.907904

31 Jul 2015 : Clinical Research

Expression of EGFR Is Closely Related to Reduced 3-Year Survival Rate in Chinese Female NSCLC

Guangyuan Sun, Bing Liu, [...] Jin He, Xuewei Zhao, Bing Li - Show fewer authors

DOI: 10.12659/MSM.894786

23 Apr 2015 : Clinical Research

Expression of miR-148/152 Family as Potential Biomarkers in Non-Small-Cell Lung Cancer

Li Li, Ye-ye Chen, [...] Shan-qing Li, Cheng Huang, Ying-zhi Qin - Show fewer authors

DOI: 10.12659/MSM.892940

12 Nov 2015 : Case report

An Autopsy Case of Rapidly Progressing Spindle Cell Carcinoma of the Lung Accompanied with Intratumor Hemorrhage

Jun-ichiro Kida, Nobuhiro Kanaji, [...] Sosuke Kishi, Katsumi Imaida, Shuji Bandoh - Show fewer authors

DOI: 10.12659/AJCR.894443

10 Sep 2015 : Clinical Research

Association of CD44 Gene Polymorphism with Survival of NSCLC and Risk of Bone Metastasis

Yaosheng Liu, Haifeng Qing, [...] Xiuyun Su, Cheng Wang, Zhou Li, Shubin Liu - Show fewer authors

DOI: 10.12659/MSM.894357

27 Aug 2015 : Laboratory Research

Rhizoma Paridis Saponins Induces Cell Cycle Arrest and Apoptosis in Non-Small Cell Lung Carcinoma A549 Cells

Jue Zhang, Yixi Yang, [...] Lei Lei, Mengliang Tian - Show fewer authors

DOI: 10.12659/MSM.895084

25 Aug 2015 : Clinical Research

Downregulation of MiR-30a is Associated with Poor Prognosis in Lung Cancer

Ruixue Tang, Lu Liang, [...] Dianzhong Luo, Zhenbo Feng, Qiuxia Huang, Rongquan He, Tingqing Gan, Lihua Yang, Gang Chen - Show fewer authors

DOI: 10.12659/MSM.894372