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Medical Science Monitor Basic Research


eISSN: 1643-3750

Utility of Magnetic Resonance Imaging in Diagnosis of Prenatal Non-Visualization of the Fetal Gallbladder: A Case-Series Study

Yuanhe Wang, Jinling Zhou, Meixiang Deng, Xiaomiao Xiang, Xiaojun Zhu

Department of Obstetrics, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland)

Med Sci Monit 2021; 27:e927474

DOI: 10.12659/MSM.927474

Available online: 2020-11-02

Published: 2021-01-05


BACKGROUND: This study aimed to assess the utility of magnetic resonance imaging (MRI) in the diagnosis of prenatal non-visualization of the fetal gallbladder (PNVGB).
MATERIAL AND METHODS: The clinical data of 32 pregnant women with PNVGB who underwent MRI examination during the second and third trimester of pregnancy were collected and their outcomes were analyzed.
RESULTS: MRI showed that 26 patients (81.3%) had isolated PNVGB and 6 (18.8%) had additional malformations. In 26 patients with isolated PNVGB, 7 were found in the gallbladder on MRI and 4 were found on subsequent ultrasonography. One patient had termination of pregnancy (TOP) and 1 patient was lost to follow-up; the remaining 24 patients were known to deliver a healthy child. Among the 6 patients with additional malformations, 3 terminated their pregnancies due to combined severe abnormalities: 1 patient with horseshoe kidney and 1 with fetal echogenic bowel both had a healthy child, while 1 with fetal growth restriction (FGR) delivered a child who walked on tiptoe.
CONCLUSIONS: MRI contributes to identifying PNVGB detected or suspected by ultrasonography.

Keywords: gallbladder diseases, Magnetic Resonance Imaging, Prenatal Diagnosis