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25 December 2020 : Clinical Research

Comparison of the Clinical Efficacy of 3 Surgical Methods for Treating Spinal Tuberculosis in Children

Weidong Liang1ACDEF, Jian Zhang1ACDEF, Zhouliang Ren1BC, Maierdan Maimaiti1B, Fulati Mamati1B, Yakefu Abulizi1B, Tao Xu1C, Rui Cao1C, Jun Sheng1AE*, Weibin Sheng1AE

DOI: 10.12659/MSM.926142

Med Sci Monit 2020; 26:e926142


BACKGROUND: This study aimed to investigate the safety and clinical efficacy of 3 different surgical methods for treating spinal tuberculosis (ST) in children.

MATERIAL AND METHODS: We reviewed the cases of 62 children with ST who were treated in our hospital from January 2010 to December 2014. In this study, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, Frankel classification of neurological function, pain visual analog scale (VAS) score, and kyphosis Cobb (k-Cobb) angle were dynamically monitored to evaluate the efficacy of different surgical methods. Complications in the patients were evaluated at 3 time points: before surgery (T1), after surgery (T2), and during final follow-up (T3). The average follow-up was 27.4 months. Twenty-two patients underwent simple anterior debridement alone or combined with internal fixation (Method A), 13 patients underwent posterior debridement alone (Method B), and 27 patients received anteroposterior debridement and bone graft fusion together with internal fixation (Method C).

RESULTS: In all 3 groups after surgery, ESR, CRP levels, VAS scores, and k-Cobb angles significantly decreased. However, compared with patients who received Methods B and C, patients who received Method A had a significant rebound in k-Cobb angle and a higher incidence of complications at the T3 time point. The overall reoperation rate during follow-up was 37.10%. Fourteen patients (22.58%) had kyphosis, 2 patients (3.23%) had tuberculosis recurrence combined with kyphosis, and other complications were reported in 5 patients (8.06%).

CONCLUSIONS: Considering the incidence of complications and level of postoperative biochemical indicators, we concluded that caution should be exercised in using an anterior approach to treat pediatric ST.

Keywords: Child, general surgery, Spine, Tuberculosis


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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750