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26 September 2019 : Clinical Research

Safety of Cement Distribution Patterns in Metastatic Vertebral Tumors: A Retrospective Study

Zhangzhe Zhou1ABDEF*, Yimeng Wang1BCF, Zhiyong Sun1BF, Zhonglai Qian1AD

DOI: 10.12659/MSM.918212

Med Sci Monit 2019; 25:7228-7234

Abstract

BACKGROUND: Kyphoplasty (KP) is a palliative treatment for patients with metastatic vertebral tumors. The distribution pattern of cement affects safety and efficacy. The distribution pattern of cement has not been previously reported for patients with metastatic vertebral tumors.

MATERIAL AND METHODS: From January 2013 to December 2017, patients with metastatic vertebral tumors who met our criteria were divided into cement fusion (n=91) and separation (n=97) groups. Visual analogue scale (VAS) and middle vertebral height (MVH) were evaluated preoperatively, postoperatively, and 1 year after surgery. Spinal Instability Neoplastic Score, fluoroscopy time, operation time, cement volume, cement leakage, and vertebral fractures were recorded and evaluated.

RESULTS: Compared with the fusion group, the separation group had significantly different (P<0.001) operation time, fluoroscopy time, and cement volume. Compared with preoperative status, VAS and MVH were significantly improved 3 days postoperatively and 1 year postoperatively in both groups (P<0.001). The difference in cement leakage between the 2 groups (P<0.05) and in the number of adjacent vertebral fractures between the 2 groups (P<0.05) were significant.

CONCLUSIONS: The distribution patterns of the bone cement had a good analgesic effect and preventive effect on vertebral collapse. However, the separation of bone cement may be safer.

Keywords: Bone Cements, kyphoplasty, Palliative Care, Spine

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750