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22 January 2019 : Meta-Analysis  

Identification of Recent Trends in Research on Vitamin D: A Quantitative and Co-Word Analysis

Aolin Yang1ABCDEF, Qingqing Lv1ABCDF, Feng Chen2B, Difei Wang2DG, Ying Liu3DG, Wanying Shi1AD*

DOI: 10.12659/MSM.913026

Med Sci Monit 2019; 25:643-655

Abstract

BACKGROUND: In recent years, many studies on vitamin D have been published. We combed these data for hot spot analyses and predicted future research topic trends.

MATERIAL AND METHODS: Articles (4625) concerning vitamin D published in the past 3 years were selected as a study sample. Bibliographic Items Co-occurrence Matrix Builder (BICOMB) software was used to screen high-frequency Medical Subject Headings (MeSH) terms and construct a MeSH terms-source article matrix and MeSH terms co-occurrence matrix. Then, Graphical Clustering Toolkit (gCLUTO) software was employed to analyze the matrix by double-clustering and visual analysis to detect the trends on the subject.

RESULTS: Ninety high-frequency major MeSH terms were obtained from 4625 articles and divided into 5 clusters, and we generated a visualized matrix and a mountain map. Strategic coordinates were established by the co-occurrence matrix of the MeSH terms based on the above classification, and the 5 clusters described above were further divided into 7 topics. We classified the vitamin D-related diseases into 12 categories and analyzed their distribution.

CONCLUSIONS: The analysis of strategic coordinates revealed that the epidemiological study of vitamin D deficiency and vitamin D-related diseases is a hot research topic. The use of vitamin D in the prevention and treatment of some diseases, especially diabetes, was found to have a significant potential future research value.

Keywords: Bibliometrics, Diabetes Mellitus, Neoplasms, Vitamin D, Cluster Analysis, Medical Subject Headings, Publications, Research, Software, Vitamin D Deficiency, Vitamins

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750