Diagnostic and Outcome Prediction Value of Transthoracic Impedance Cardiography in Heart Failure Patients During Heart Failure Flare-Ups
Saulius Sadauskas, Albinas Naudžiūnas, Alvydas Unikauskas, Edita Mašanauskienė, Andrius Ališauskas, Giedrė Bakšytė, Andrius Macas
Clinical Department of Internal Diseases, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
Med Sci Monit 2018; 24:6573-6578
This study aimed at evaluating the diagnostic and outcome prediction value of transthoracic impedance cardiography (ICG) in heart failure (HF) patients admitted for in-hospital treatment due to flare-ups of their condition.
MATERIAL AND METHODS: In total, 120 patients of intensive care units who were admitted due to HF flare-ups were involved to the study. The findings of ICG were compared to data obtained by other methods used for diagnosing HF.
RESULTS: Statistically significant (p<0.001) results were obtained when evaluating differences in ICG data between admission and discharge from the intensive care unit. In addition, a correlation was detected between brain natriuretic peptide (BNP) and thoracic fluid content index (r=0.4, p<0.001). Differences in ICG values, and BNP data emerged after the participants were grouped according to NYHA classes (p<0.05). The evaluation of lethal outcome during 6 months after the discharge yielded statistically significant results: BNP ≥350 pg/mL (Odds Ratio (OR) 4.4), thoracic fluid content ≥34 1/kOhm (OR 4.3), and systolic time ratio ≥0.55 (OR 2.9), p<0.05.
CONCLUSIONS: ICG data might be applied for the diagnosis and prognosis of HF, although the links between ICG and HF need further evaluation.
Keywords: Cardiography, Impedance, Heart Failure, Natriuretic Peptide, Brain