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02 May 2018 : Clinical Research  

Bovine Acellular Dermal Matrix for Levator Lengthening in Thyroid-Related Upper-Eyelid Retraction

Jing Sun12ABE, Xingtong Liu12BC, Yidan Zhang12B, Yazhuo Huang12B, Sisi Zhong12D, Sijie Fang12D, Ai Zhuang12E, Yinwei Li12F, Huifang Zhou12AG, Xianqun Fan12A*

DOI: 10.12659/MSM.909306

Med Sci Monit 2018; 24: CLR2728-2734

Abstract

BACKGROUND: Eyelid retraction is the most common and often the first sign of thyroid eye disease (TED). Upper-eyelid retraction causes both functional and cosmetic problems. In order to correct the position of the upper eyelid, surgery is required. Many procedures have demonstrated good outcomes in mild and moderate cases; however, unpredictable results have been obtained in severe cases. Dryden introduced an upper-eyelid-lengthening procedure, which used scleral grafts, but outcomes were unsatisfactory. A new technique is introduced in this study as a reasonable alternative for TED-related severe upper-eyelid retraction correction.

MATERIAL AND METHODS: An innovative technique for levator lengthening using bovine acellular dermal matrix as a spacer graft is introduced for severe upper-eyelid retraction secondary to TED. Additionally, 2 modifications were introduced: the fibrous cords scattered on the surface of the levator aponeurosis were excised and the orbital fat pad anterior to the aponeurosis was dissected and sutured into the skin closure in a “skin-tarsus-fat-skin” fashion.

RESULTS: The modified levator-lengthening surgery was performed on 32 eyelids in 26 patients consisting of 21 women and 5 men (mean age, 37.8 years; age range, 19–67 years). After corrective surgery, the average upper margin reflex distance was lowered from 7.7±0.85 mm to 3.3±0.43 mm. Eighteen cases (69%) had perfect results, while 6 cases (23%) had acceptable results.

CONCLUSIONS: A modified levator-lengthening procedure using bovine acellular dermal matrix as a spacer graft ameliorated both the symptoms and signs of severe upper-eyelid retraction secondary to TED. This procedure is a reasonable alternative for correction of TED-related severe upper-eyelid retraction.

Keywords: acellular dermis, Eyelid Diseases, Graves Ophthalmopathy

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750