Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

05 April 2018 : Laboratory Research  

The Effects of Left Ventricular Assist Device Support Level on the Biomechanical States of Aortic Valve

Qi Zhang1BEF, Bin Gao1CDEFG*, Chang Yu1G

DOI: 10.12659/MSM.906903

Med Sci Monit 2018; 24: MET2003-2017

Abstract

BACKGROUND: Although aortic valve disease caused by left ventricular assist device (LVAD) support has attracted more and more attention, the precise biomechanical effects of LVAD support level on the aortic valve are still unclear.

MATERIAL AND METHODS: A structural finite element models study was conducted using an ideal aortic valve geometric model. Four different study conditions were designed, according to the reduction of the open duration of the aortic valve. The isotropic hyperelastic constitutive equation was chosen to reflect the mechanical property of the leaflets. The distribution of the stress, strain, and transient dynamics of the leaflet were calculated.

RESULTS: Along with the increase of LVAD support level, the open duration of the aortic valve was also reduced by the increase of LVAD support (low support level case 0.23 seconds versus middle support level case 0.2 seconds versus high support level case 0.14 seconds). Moreover, along with the increase of support mode of LVAD, the von Mises stress in most leaflet areas was increased from the low stress level (0–0.4 MPa) to the middle region (0.4–0.8 MPa). Once the leaflets were continuously closed, the high stress level (larger than 0.8 MPa) was observed. In contrast, the support level of LVAD only had slight effects on the distribution of von Mises strain. According to the aforementioned results, maintaining the open duration of aortic valve longer than 0.2 seconds could achieve better performance of biomechanical states of leaflets.

CONCLUSIONS: This study could provide useful information on the determination of optimal LVAD support strategy.

Keywords: Aortic Valve, Biomechanical Phenomena, Finite Element Analysis

Comments

Editorial

01 January 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Patients

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

SARS-CoV-2/COVID-19

25 January 2022 : Editorial  

Editorial: The 2022 World Health Organization (WHO) Priority Recommendations and Response to the Omicron Va...

Med Sci Monit In Press; DOI: 10.12659/MSM.936199  

25 January 2022 : Clinical Research  

Experience of the Polish Medical Air Rescue Service During the First Year of the COVID-19 Pandemic and Meas...

Med Sci Monit In Press; DOI: 10.12659/MSM.935474  

11 January 2022 : Clinical Research  

A Remote Questionnaire-Based Study to Compare Alcohol Use in 1030 Final-Year High School Students in Split-...

Med Sci Monit In Press; DOI: 10.12659/MSM.935567  

31 December 2021 : Clinical Research  

A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus...

Med Sci Monit 2021; 27:e935075

In Press

27 Jan 2022 : Clinical Research  

Retrospective Study of the Association Between Platelet-to-Lymphocyte Ratio in Patients with Acute Coronary...

Med Sci Monit In Press; DOI: 10.12659/MSM.935002  

25 Jan 2022 : Editorial  

Editorial: The 2022 World Health Organization (WHO) Priority Recommendations and Response to the Omicron Va...

Med Sci Monit In Press; DOI: 10.12659/MSM.936199  

25 Jan 2022 : Clinical Research  

Experience of the Polish Medical Air Rescue Service During the First Year of the COVID-19 Pandemic and Meas...

Med Sci Monit In Press; DOI: 10.12659/MSM.935474  

24 Jan 2022 : Clinical Research  

Causes of Lower Respiratory Tract Infections and the Use of Diagnostic Biomarkers in Blood Samples from Chi...

Med Sci Monit In Press; DOI: 10.12659/MSM.934889  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

05 Mar 2020 : Clinical Research  

The Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease ...

DOI :10.12659/MSM.923549

Med Sci Monit 2020; 26:e923549

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750