Scimago Lab
powered by Scopus
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


eISSN: 1643-3750

Efficacy of Strain Elastography in Diagnosis and Staging of Acute Appendicitis in Pediatric Patients

Harun Arslan, Zülküf Akdemir, Alpaslan Yavuz, Fahri Gökçal, Cemal Parlakgümüş, Necat İslamoglu, Hüseyin Akdeniz

Department of Radiology, Van Yuzuncu Yıl University Dursun Odabası Medical Center, Van, Turkey

Med Sci Monit 2018; 24: CLR855-862

DOI: 10.12659/MSM.905927

Available online: 2018-02-11

Published: 2018-02-11


BACKGROUND: In the present study, the role and efficiency of strain elastography (SE) were evaluated in diagnosis and staging of acute appendicitis in pediatric patients.
MATERIAL AND METHODS: We enrolled 225 pediatric patients with suspected clinical and laboratory findings of acute appendicitis. Gray-scale sonographic findings were recorded and staging was made by the colorization method of SE imaging. Appendectomy was performed in all patients and the results of the surgical pathology were compared with the imaging findings. The sensitivity, specificity, and accuracy of SE imaging were determined in terms of evaluating the “acute appendicitis”.
RESULTS: Sonographic evaluation revealed acute appendicitis in 100 patients. Regarding the SE analysis, cases with appendicitis were classified into 3 groups as: mild (n=17), moderate (n=39), and severe (n=44). The pathological evaluation revealed 95 different stages of appendicitis and normal appendix in 5 cases: acute focal (n=10), acute suppurative (n=46), phlegmonous (n=27), and perforated (n=12), regarding the results of surgical pathology. Five patients with pathologically proven “normal” appendix were noted as “mild stage appendicitis” based on gray scale and SE analysis. In total, when gray-scale and SE results were compared with pathology results regardless of the stage of appendicitis, sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rates were 96%, 96%, 95%, 96.8%, and 96%, respectively. No statistically significant difference was detected between other groups (P<0.05).
CONCLUSIONS: In acute appendicitis, the use of SE imaging as a supportive method for the clinical approach can be useful in diagnosis, and its results are closely correlated with the histopathologic stage of appendix inflammation.

Keywords: appendicitis, Elasticity Imaging Techniques, Pediatrics