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13 December 2017 : Laboratory Research

Dynamic Monitoring of Erythrocyte Distribution Width (RDW) and Platelet Distribution Width (PDW) in Treatment of Acute Myocardial Infarction

Jian Yu1CEF, Li Wang1B, Yuchong Peng2D, Mingjie Xiong3E, Xiaozhong Cai1F, Juan Luo1C, Minghao Zhang1AEG*

DOI: 10.12659/MSM.904916

Med Sci Monit 2017; 23:5899-5906

Abstract

BACKGROUND: This study investigated the role of erythrocyte distribution width (RDW) and platelet distribution width (PDW) in evaluating the treatment efficacy for acute myocardial infarction (AMI).

MATERIAL AND METHODS: A total of 120 AMI patients receiving conventional myocardial infarction treatment were included. The patients were divided into an effective group and an ineffective group based on treatment efficacy. The RDW and PDW were measured before and after treatment. We used the independent samples t test, chi-square test, logistic regression, and ROC curves for analysis.

RESULTS: The change and change rate of RDW and PDW were significantly improved (p<0.01) and the positive change rate of RDW, PDW, and RDW + PDW were significantly lower in the effective group compared with those in the ineffective group (p<0.01). The change and change rate of RDW and PDW are independent factors for treatment efficacy evaluation (p<0.05). ROC curve analysis showed that the changes and change rate of RDW and PDW were all significant in evaluating treatment efficacy (p<0.05).

CONCLUSIONS: The change and change rate of RDW and PDW or their combination can be used to evaluate treatment efficacy; however, the absolute value of RDW and PDW are not as significant.

Keywords: Aftercare, Blood Platelets, Erythrocyte Indices, Myocardial Infarction

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750